Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PrpT-parD/ParE-RHH
Location 163687..164212 Replicon plasmid pLG26p2
Accession NZ_CP045061
Organism Salmonella enterica subsp. enterica serovar Muenchen strain LG26

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag SMLG26_RS01055 Protein ID WP_079953242.1
Coordinates 163687..163977 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag SMLG26_RS01060 Protein ID WP_057394653.1
Coordinates 163970..164212 (-) Length 81 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMLG26_RS01030 158911..159216 - 306 WP_057394657.1 antibiotic biosynthesis monooxygenase -
SMLG26_RS01035 159293..160186 - 894 WP_153789529.1 hypothetical protein -
SMLG26_RS01040 160210..161400 - 1191 WP_097361620.1 MFS transporter -
SMLG26_RS01045 161412..162518 - 1107 WP_097361621.1 ThiF family adenylyltransferase -
SMLG26_RS01050 162764..163438 + 675 WP_057394654.1 metalloregulator ArsR/SmtB family transcription factor -
SMLG26_RS01055 163687..163977 - 291 WP_079953242.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SMLG26_RS01060 163970..164212 - 243 WP_057394653.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
SMLG26_RS01065 164473..165438 + 966 WP_057394652.1 DNA-binding protein -
SMLG26_RS01070 165525..166292 + 768 WP_097361665.1 3'-5' exonuclease -
SMLG26_RS01075 166971..168059 - 1089 WP_097361622.1 transcriptional regulator -
SMLG26_RS01080 168771..168989 + 219 WP_079953237.1 type II toxin-antitoxin system antitoxin CcdA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..270863 270863


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 14294.15 Da        Isoelectric Point: 5.5500

>T141155 WP_079953242.1 NZ_CP045061:c163977-163687 [Salmonella enterica subsp. enterica serovar Muenchen]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFF

Download         Length: 291 bp

>T141155 NZ_CP059840:2140398-2140500 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 11939.32 Da        Isoelectric Point: 5.5500

>AT141155 WP_057394653.1 NZ_CP045061:c164212-163970 [Salmonella enterica subsp. enterica serovar Muenchen]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F

Download         Length: 243 bp

>AT141155 NZ_CP059840:c2140538-2140270 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGGGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References