Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PrpT-parD/ParE-RHH
Location 163700..164225 Replicon plasmid pLG24p2
Accession NZ_CP045054
Organism Salmonella enterica subsp. enterica serovar Muenchen strain LG24

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag SMLG24_RS01040 Protein ID WP_079953242.1
Coordinates 163700..163990 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag SMLG24_RS01045 Protein ID WP_057394653.1
Coordinates 163983..164225 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SMLG24_RS01015 158924..159229 - 306 WP_057394657.1 antibiotic biosynthesis monooxygenase -
SMLG24_RS01020 159306..160199 - 894 WP_153789529.1 hypothetical protein -
SMLG24_RS01025 160223..161413 - 1191 WP_097361620.1 MFS transporter -
SMLG24_RS01030 161425..162531 - 1107 WP_097361621.1 ThiF family adenylyltransferase -
SMLG24_RS01035 162777..163451 + 675 WP_057394654.1 metalloregulator ArsR/SmtB family transcription factor -
SMLG24_RS01040 163700..163990 - 291 WP_079953242.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SMLG24_RS01045 163983..164225 - 243 WP_057394653.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
SMLG24_RS01050 164486..165451 + 966 WP_057394652.1 DNA-binding protein -
SMLG24_RS01055 165538..166305 + 768 WP_097361665.1 3'-5' exonuclease -
SMLG24_RS01060 166984..168072 - 1089 WP_097361622.1 transcriptional regulator -
SMLG24_RS01065 168784..169002 + 219 WP_079953237.1 type II toxin-antitoxin system antitoxin CcdA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..270881 270881


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 14294.15 Da        Isoelectric Point: 5.5500

>T141145 WP_079953242.1 NZ_CP045054:c163990-163700 [Salmonella enterica subsp. enterica serovar Muenchen]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFF

Download         Length: 291 bp

>T141145 NZ_CP059839:c59707-59420 [Escherichia coli]
ATGAGGTATCAGGTAAAATTCAGGGAAGATGCGCTGAAAGAGTGGCAAAAACTGGACAAGACTATTCAGCAACAGTTTGC
GAAAAAGCTAAAAAAGTGCTGTGACAATCCGCATATTCCTTCCGCAAAACTGCGCGGGATAAAGGACTGCTACAAAATAA
AATTACGTGCGTCAGGTTTACGCCTGGTCTATCAGGTGATTGACGAACAATTAATTATCGCTGTTGTAGCAGTGGGTAAA
CGTGAGCGCAGTGACGTTTATAATCTTGCCAGTGAAAGAATGAGATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 11939.32 Da        Isoelectric Point: 5.5500

>AT141145 WP_057394653.1 NZ_CP045054:c164225-163983 [Salmonella enterica subsp. enterica serovar Muenchen]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F

Download         Length: 243 bp

>AT141145 NZ_CP059839:c59955-59704 [Escherichia coli]
ATGCCTAACATTATTCTCAGTGATACAAGCGCCAGTGTCAGCGAGCTGAAGAAAAATCCGATGGCGACAGTCAGCGCCGG
TGATGGTTTCCCGGTCGCTATCCTGAACCGTAATCAGCCTGCTTTCTACTGTGTACCCGCAGAGCTGTACGAAAAGATGC
TCGATGCCCTGGACGATCAGGAGCTGGTTAAACTGGTAGCCGAACGCAGCAACCAACCGCTGCATGATGTGGACTTGGAT
AAATACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References