Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1836628..1836773 Replicon chromosome
Accession NZ_CP045015
Organism Klebsiella pneumoniae subsp. pneumoniae strain BK13048

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1836664..1836766 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1836628..1836773 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F9865_RS09090 1831758..1833818 + 2061 WP_004151449.1 oligopeptidase B -
F9865_RS09095 1833822..1834481 - 660 WP_002911407.1 exodeoxyribonuclease X -
F9865_RS09100 1834560..1834790 - 231 WP_002911406.1 DNA polymerase III subunit theta -
F9865_RS09105 1834903..1835277 + 375 WP_004151448.1 CopC domain-containing protein YobA -
F9865_RS09110 1835281..1836150 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
F9865_RS09115 1836167..1836505 + 339 WP_009307539.1 YebY family protein -
- 1836628..1836773 - 146 - - Antitoxin
- 1836664..1836766 + 103 - - Toxin
F9865_RS09125 1837142..1837285 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
F9865_RS09130 1837390..1838358 - 969 WP_004151446.1 VirK/YbjX family protein -
F9865_RS09135 1838515..1839168 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
F9865_RS09140 1839165..1839356 - 192 WP_002911395.1 YebW family protein -
F9865_RS09145 1839454..1839693 - 240 WP_002911393.1 YebV family protein -
F9865_RS09150 1839809..1841242 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T141105 NZ_CP045015:1836664-1836766 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT141105 NZ_CP045015:c1836773-1836628 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References