Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacAT/GNAT-DUF1778 |
Location | 2467953..2468698 | Replicon | chromosome |
Accession | NZ_CP045008 | ||
Organism | Proteus terrae subsp. cibarius strain ZF2 |
Toxin (Protein)
Gene name | tacT | Uniprot ID | - |
Locus tag | F9282_RS11850 | Protein ID | WP_075673025.1 |
Coordinates | 2468207..2468698 (+) | Length | 164 a.a. |
Antitoxin (Protein)
Gene name | tacA | Uniprot ID | - |
Locus tag | F9282_RS11845 | Protein ID | WP_075673024.1 |
Coordinates | 2467953..2468219 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
F9282_RS11810 | 2463616..2464098 | + | 483 | WP_006533151.1 | flagellar basal body-associated protein FliL | - |
F9282_RS11815 | 2464104..2465132 | + | 1029 | WP_088495228.1 | flagellar motor switch protein FliM | - |
F9282_RS11820 | 2465125..2465535 | + | 411 | WP_023581830.1 | flagellar motor switch protein FliN | - |
F9282_RS11825 | 2465539..2465985 | + | 447 | WP_023581829.1 | flagellar biosynthetic protein FliO | - |
F9282_RS11830 | 2466042..2466755 | + | 714 | WP_171455369.1 | flagellar type III secretion system pore protein FliP | - |
F9282_RS11835 | 2466771..2467040 | + | 270 | WP_069367481.1 | flagellar biosynthesis protein FliQ | - |
F9282_RS11840 | 2467046..2467828 | + | 783 | WP_088495227.1 | flagellar type III secretion system protein FliR | - |
F9282_RS11845 | 2467953..2468219 | + | 267 | WP_075673024.1 | DUF1778 domain-containing protein | Antitoxin |
F9282_RS11850 | 2468207..2468698 | + | 492 | WP_075673025.1 | GNAT family N-acetyltransferase | Toxin |
F9282_RS11855 | 2468784..2469728 | - | 945 | WP_156733628.1 | flagellar hook-associated protein FlgL | - |
F9282_RS11860 | 2469760..2471403 | - | 1644 | WP_156733630.1 | flagellar hook-associated protein FlgK | - |
F9282_RS11865 | 2471521..2472507 | - | 987 | WP_088495222.1 | flagellar assembly peptidoglycan hydrolase FlgJ | - |
F9282_RS11870 | 2472507..2473613 | - | 1107 | WP_088495221.1 | flagellar basal body P-ring protein FlgI | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 164 a.a. Molecular weight: 18228.15 Da Isoelectric Point: 10.3194
>T141093 WP_075673025.1 NZ_CP045008:2468207-2468698 [Proteus terrae subsp. cibarius]
MGKVTAPEPLSNSHEVADFYSSENVLDNWIKQRGLKNQFLGASRTFVVCEKNKKRVVGYYSLATGSVNHTEAMSHIRRNM
PDPIPVIILARLAVDKTFHGKGLGADLLRDAVLRCHHVAENIGVRAIMVHALTENAKHFYLHHGFKASSTQDKILFLALK
KKI
MGKVTAPEPLSNSHEVADFYSSENVLDNWIKQRGLKNQFLGASRTFVVCEKNKKRVVGYYSLATGSVNHTEAMSHIRRNM
PDPIPVIILARLAVDKTFHGKGLGADLLRDAVLRCHHVAENIGVRAIMVHALTENAKHFYLHHGFKASSTQDKILFLALK
KKI
Download Length: 492 bp
>T141093 NZ_CP059767:c22869-22612 [Enterococcus faecium]
ATGATTAAGGCTTGGTCTGATGATGCTTGGGATGATTATCTTTATTGGCATGAGCAAGGAAACAAAAGCAATATAAAAAA
GATTAACAAGTTAATAAAAGATATCGATCGTTCCCCCTTTGCTGGATTAGGAAAACCTGAGCCATTAAAGCATGATTTAT
CTGGAAAATGGTCCAGAAGAATTACAGATGAACATAGACTGATATATAGAGTTGAAAATGAAACGATATTTATTTATTCT
GCAAAAGATCACTATTAA
ATGATTAAGGCTTGGTCTGATGATGCTTGGGATGATTATCTTTATTGGCATGAGCAAGGAAACAAAAGCAATATAAAAAA
GATTAACAAGTTAATAAAAGATATCGATCGTTCCCCCTTTGCTGGATTAGGAAAACCTGAGCCATTAAAGCATGATTTAT
CTGGAAAATGGTCCAGAAGAATTACAGATGAACATAGACTGATATATAGAGTTGAAAATGAAACGATATTTATTTATTCT
GCAAAAGATCACTATTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10111.62 Da Isoelectric Point: 4.5256
>AT141093 WP_075673024.1 NZ_CP045008:2467953-2468219 [Proteus terrae subsp. cibarius]
MKADVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK
MKADVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK
Download Length: 267 bp
>AT141093 NZ_CP059767:c23131-22862 [Enterococcus faecium]
ATGGAAGCAGTAGCTTATTCAAATTTCCGCCAAAATTTACGTAGTTATATGAAACAAGTTAATGAGGATGCTGAAACACT
TATTGTAACAAGTAAAGATGTAGAAGATACAGTTGTTGTATTATCAAAAAGAGATTATGATTCTATGCAAGAAACGTTGA
GAACACTTTCTAATAATTACGTCATGGAAAAAATTCGTCGAGGAGATGAACAATTCTCCAAAGGTGCATTTAAAACACAT
GACTTAATCGAGGTTGAATCTGATGATTAA
ATGGAAGCAGTAGCTTATTCAAATTTCCGCCAAAATTTACGTAGTTATATGAAACAAGTTAATGAGGATGCTGAAACACT
TATTGTAACAAGTAAAGATGTAGAAGATACAGTTGTTGTATTATCAAAAAGAGATTATGATTCTATGCAAGAAACGTTGA
GAACACTTTCTAATAATTACGTCATGGAAAAAATTCGTCGAGGAGATGAACAATTCTCCAAAGGTGCATTTAAAACACAT
GACTTAATCGAGGTTGAATCTGATGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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