Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpIK/PemK(toxin)
Location 312955..313541 Replicon chromosome
Accession NZ_CP044990
Organism Deinococcus sp. AJ005

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag DAAJ005_RS03565 Protein ID WP_151845910.1
Coordinates 312955..313305 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpI Uniprot ID -
Locus tag DAAJ005_RS03570 Protein ID WP_151845911.1
Coordinates 313302..313541 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DAAJ005_RS03535 308459..309094 - 636 WP_151845905.1 hypothetical protein -
DAAJ005_RS03540 309257..310165 - 909 WP_151845906.1 ROK family protein -
DAAJ005_RS03545 310219..310521 - 303 WP_151845907.1 hypothetical protein -
DAAJ005_RS03550 310518..310997 - 480 WP_151845908.1 acyl-CoA thioesterase -
DAAJ005_RS03555 311199..311504 + 306 WP_151848367.1 cell division protein FtsB -
DAAJ005_RS03560 311622..312938 - 1317 WP_151845909.1 thymidine phosphorylase -
DAAJ005_RS03565 312955..313305 - 351 WP_151845910.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
DAAJ005_RS03570 313302..313541 - 240 WP_151845911.1 ChpI protein Antitoxin
DAAJ005_RS03575 313560..314525 - 966 WP_151845912.1 YafY family transcriptional regulator -
DAAJ005_RS03580 314597..315112 + 516 WP_151845913.1 DinB family protein -
DAAJ005_RS03585 315143..315403 + 261 WP_151845914.1 DUF3224 domain-containing protein -
DAAJ005_RS03590 315400..315684 + 285 WP_151845915.1 DUF1905 domain-containing protein -
DAAJ005_RS03595 315707..316228 + 522 WP_151845916.1 DinB family protein -
DAAJ005_RS03600 316228..316743 + 516 WP_151845917.1 DinB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12676.58 Da        Isoelectric Point: 5.6693

>T141083 WP_151845910.1 NZ_CP044990:c313305-312955 [Deinococcus sp. AJ005]
VKRGEVWDIEYPLTQRQNAEAYGHGPVVVVSADDFNASAIQTVLVAVLTSNIRLQAAPGNVLLLADEHNGLAQDSVLNVS
QVLVVDKTRLERCRGQLNRISLDLLDMGLKLVFALK

Download         Length: 351 bp

>T141083 NZ_CP059756:c19186-18323 [Enterococcus faecium]
ATGGCAAATATAGTCAATTTTACTGACAAACAATTTGAGAATCGCTTAAATGATAATTTAGAAGAATTGATTCAAGGAAA
AAAAGCGGTTGAATCGCCAACCGCTTTTTTACTTGGTGGGCAACCAGGGTCAGGGAAAACCAGTTTGCGATCAGCAATTT
TTGAAGAAACACAAGGGAATGTTATTGTCATTGATAATGATACCTTTAAACAACAGCACCCTAATTTTGATGAACTAGTG
AAACTTTATGAAAAAGACGTAGTAAAACACGTTACCCCTTATTCTAATCGCATGACAGAAGCGATCATAAGCCGTTTGAG
CGATCAAGGGTATAATTTGGTGATCGAAGGTACAGGACGAACAACAGACGTTCCTATTCAAACCGCAACAATGCTTCAAG
CCAAAGGTTATGAAACAAAAATGTATGTCATGGCAGTACCTAAAATCAACTCATATTTAGGAACAATTGAACGATATGAA
ACCATGTATGCAGATGATCCAATGACAGCCAGGGCAACACCAAAACAAGCGCATGATATTGTTGTCAAAAACTTACCGAC
CAATTTAGAAACCCTTCATAAAACGGGCTTATTTAGCGATATAAGGCTATATAACAGAGAAGGAGTAAAACTCTATTCAA
GTTTGGAAACACCTTCTATTAGTCCAAAAGAAACCTTAGAAAAAGAATTGAATCGTAAAGTATCAGGGAAAGAAATTCAA
CCGACTTTAGAACGAATAGAGCAAAAAATGGTTCTAAATAAACACCAAGAGACACCTGAATTTAAAGCAATTCAACAAAA
ATTGGAAAGCTTGCAGCCACCTACACCACCAATACCCAAAACACCTAAACTTCCAGGTATTTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8849.81 Da        Isoelectric Point: 4.5659

>AT141083 WP_151845911.1 NZ_CP044990:c313541-313302 [Deinococcus sp. AJ005]
MKTAISLADALYRRAEQFAQGQRLSRSELYARALEEFLERNEGQTVTAQLNAVYANEDSSLSPALAELGFEALRRQNAE

Download         Length: 240 bp

>AT141083 NZ_CP059756:c19460-19188 [Enterococcus faecium]
ATGGCAGTTACGTATGAAAAAACATTTGAAATAGAGATCATTAACGAATTATCGGCAAGCGTTTATAATCGAGTATTAAA
CTATGTTTTGAACCATGAATTAAATAAAAATGACTCTCAATTATTGGAAGTCAATTTATTAAACCAATTAAAGCTTGCAA
AACGTGTAAATCTTTTTGATTATTCTTTAGAAGAATTACAAGCCGTTCATGAGTATTGGCGGTCAATGAATCGTTACTCA
AAACAAGTTTTGAATAAAGAGAAAGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References