Detailed information of TA system TA141068

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 24352..24977
• Replicon: plasmid PNCS007087 strain 14[5]12:i:-
• Accession: NZ_CP044959
• Organism: Salmonella enterica subsp. enterica serovar 14[5]12:i:- strain PNCS007087

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: E5O00_RS24940
• Protein ID: WP_000911322.1
• Coordinates: 24579..24977 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: E5O00_RS24935
• Protein ID: WP_000450265.1
• Coordinates: 24352..24579 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E5O00_RS24935	24352..24579	+	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin
E5O00_RS24940	24579..24977	+	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
E5O00_RS24945	24986..27148	-	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
E5O00_RS24950	27525..28256	-	732	WP_000782438.1	complement resistance protein TraT	-
E5O00_RS24955	28292..28786	-	495	WP_010999946.1	entry exclusion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93838	93838

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-71)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 17065.17 Da
• Isoelectric Point: 12.9205

>T141068 WP_000911322.1 NZ_CP044959:24579-24977 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 399 bp

>T141068 NZ_CP059738:6223101-6223397 [Pseudomonas sp. 29A]
ATGACCTATAACCTTGAATTTGATCGTCGTGCTTTAAAGGAGTGGAACAAACTCGGCGATACGGTTCGCCACCAGTTCAA
GAAGAAACTCACAGAGGTATTGGAGAATCCTCGAATAGAAGCCAATCGACTTCGCGAGCTCCCGGATTGCTACAAAGTGA
AGCTGAAAAGCGCTGGCTATCGCCTGATCTATCAGGTCCTTGATCAAGAGATTGTGGTGTTCGTAATCGCAATCGGGAAG
CGAGAGAGAGAAGCTGCTTACGAGGTTGCGCAGGACCGTCTTTCGCTCCTGCCCTGA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 9759.25 Da
• Isoelectric Point: 12.6750

>AT141068 WP_000450265.1 NZ_CP044959:24352-24579 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 228 bp

>AT141068 NZ_CP059738:6222872-6223111 [Pseudomonas sp. 29A]
ATGGCCTCCATCAACATTCGCATCGACGATGATCTGAAGCAGCGCTCCTTCGCCGAACTGGAAAAGCTGGGAGTAACCCC
CTCAGAGCTTTTGCGCCAGACACTCCAATACGTCGCCGAGCGAGGCAAGCTACCCTTCAAAGCAGCATTGCTCAGCGAGG
AAGATGAAGTACTCATAGCCGTAGTCACCGAACGCCTCGCGGCACCTCAACGAGTCAAGGTAAGTCTGGATGACCTATAA