Detailed information of TA system TA141066

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 3659374..3660830
• Replicon: chromosome
• Accession: NZ_CP044549
• Organism: Hydrogenophaga sp. BPS33

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: F9K07_RS17045
• Protein ID: WP_159594563.1
• Coordinates: 3659374..3660216 (-)
• Length: 281 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: F9K07_RS17050
• Protein ID: WP_159596978.1
• Coordinates: 3660213..3660830 (-)
• Length: 206 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F9K07_RS17025	3654632..3655831	+	1200	WP_159594559.1	glycine betaine/L-proline ABC transporter ATP-binding protein ProV	-
F9K07_RS17030	3655899..3657065	+	1167	WP_159594560.1	glycine betaine/L-proline ABC transporter permease ProW	-
F9K07_RS17035	3657109..3658131	+	1023	WP_159594561.1	glycine betaine/L-proline ABC transporter substrate-binding protein ProX	-
F9K07_RS17040	3658250..3659275	+	1026	WP_159594562.1	glycine betaine/L-proline ABC transporter substrate-binding protein ProX	-
F9K07_RS17045	3659374..3660216	-	843	WP_159594563.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
F9K07_RS17050	3660213..3660830	-	618	WP_159596978.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
F9K07_RS17055	3661207..3661659	+	453	WP_159594564.1	NYN domain-containing protein	-
F9K07_RS17060	3661688..3662902	-	1215	WP_159596979.1	sodium/glutamate symporter	-
F9K07_RS17065	3663062..3664447	-	1386	WP_159594565.1	class II fumarate hydratase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-257)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (13-58)

Sequences

Toxin

Protein

• Length: 281 a.a.
• Molecular weight: 31005.58 Da
• Isoelectric Point: 8.4301

>T141066 WP_159594563.1 NZ_CP044549:c3660216-3659374 [Hydrogenophaga sp. BPS33]
MTRNVAASIRARLKQSASTKNQDFDLTLTHYGLERLLYRLSISPHAANYLLKGALLFSLWYDRPHRPTRDADLLGFGSDS
IDTAVSVFREICQIQVDDGIAFDSASVKGSLIRKDAGYGGVRVDLLASLDGARMALQVDIGFGDVVTPAPESVNYPVLLS
DLPAPQLRAYPKYTVVAEKFHAVCLLGMANTRMKDYFDLWVLLSEGVLERAELRSAIEATFSRRQLALPSVLPAGLSDAF
AQDATKQNQWAGFLKRNRLEQLVLSEVVARLRSEFLSLAR

Nucleotide

• Length: 843 bp

>T141066 NZ_CP059738:c2718290-2718006 [Pseudomonas sp. 29A]
ATGCAGATTAAGTGGCGACCCAAGGCTCGGGTCGAACTCTCGAAAATCCTGAAGTACATTGGCGAGCGAAATTTTGTAGC
GGCGACTGCACTTCACAAGTCCGTCGTAAAAACTACATCTGCGCTTTGTTGGCATCCACACCTGTATCGCAAAGGCCGCT
CTCCCGGCACTCGAGAGATTGTGGTAAGCCCGAACTATCTCGTCGTTTATCAAGTGGCGGACCAAATTGAGATTGTGAGC
ATCTTGCATGCGCGTCAGGAGTACCCTCGACGCGACCCCGGTTAA

Antitoxin

Protein

• Length: 206 a.a.
• Molecular weight: 22617.16 Da
• Isoelectric Point: 9.0776

>AT141066 WP_159596978.1 NZ_CP044549:c3660830-3660213 [Hydrogenophaga sp. BPS33]
MTPTSDPTLEQAVLALAEHQTLLRARDLAEHGLPRVMLSRLVSAGKLERVARGVYSLPGRSLHEHRSLAEVALLAPRSVV
CLLSALRVHGIGTQAPFEVWVAIPHNSPTPRIDQPALRVVRMSGESLTDGIEHFTIDGVKVPVFNAAKTVADCFKYRNKI
GLDVALEALRDGWSQRKLSMDALWHYATVDRVANVMRPYLESITS

Nucleotide

• Length: 618 bp

>AT141066 NZ_CP059738:c2718471-2718280 [Pseudomonas sp. 29A]
ATGATTGACCCGCTGTGCCCAGTCGTCTCGGATCTTGATCCTGAAGAACAGGCTGCGAGCTATGACCGCTGGTTCAGGGC
GGAAGTACAAGCGTCTCTCGATGATCCGCGTCCGAGTATTCCCCATGAGCAAGTGATGGAGGAAATCAATGCCTTGATGG
AATCAATGCGCAAAAGCGCTGATGCAGATTAA