Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 2524721..2526399 Replicon chromosome
Accession NZ_CP044549
Organism Hydrogenophaga sp. BPS33

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag F9K07_RS11755 Protein ID WP_159593223.1
Coordinates 2525566..2526399 (-) Length 278 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag F9K07_RS11750 Protein ID WP_159593220.1
Coordinates 2524721..2525551 (-) Length 277 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F9K07_RS11735 2520734..2522206 - 1473 WP_159593214.1 aldehyde dehydrogenase -
F9K07_RS11740 2522203..2523000 - 798 WP_159596905.1 aspartate dehydrogenase -
F9K07_RS11745 2523042..2524724 - 1683 WP_159593217.1 thiamine pyrophosphate-binding protein -
F9K07_RS11750 2524721..2525551 - 831 WP_159593220.1 IclR family transcriptional regulator Antitoxin
F9K07_RS11755 2525566..2526399 - 834 WP_159593223.1 alpha/beta hydrolase Toxin
F9K07_RS11760 2526530..2527069 - 540 WP_159596906.1 cupin domain-containing protein -
F9K07_RS11765 2527151..2527915 - 765 WP_159596907.1 SDR family oxidoreductase -
F9K07_RS11770 2527918..2528703 - 786 WP_159593226.1 ABC transporter permease -
F9K07_RS11775 2528741..2529736 - 996 WP_159596908.1 ABC transporter substrate-binding protein -
F9K07_RS11780 2529791..2530597 - 807 WP_159593229.1 ABC transporter ATP-binding protein -
F9K07_RS31570 2530811..2530981 + 171 WP_201451547.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(37-272)

Antitoxin

Transcription regulator IclR, N-terminal

(15-65)


Sequences

Toxin        


Download         Length: 278 a.a.        Molecular weight: 28472.49 Da        Isoelectric Point: 6.9599

>T141064 WP_159593223.1 NZ_CP044549:c2526399-2525566 [Hydrogenophaga sp. BPS33]
MTPLQALATFPSRTTALADGARVSYREAGSATEVTHVLLHGIGSASGSWVRQLEAAQAAQGKPVRVVAWDAPGYSGSTPV
AAEWPCTDDYAQRVWAWLDALEARAPVTLVGHSLGALMAGRAALLAPSRVQRLVLLSPAGGYGKAEPAVREQKLKDRLAT
LERLGPQGMAQARGAAMLSPGAAPDLVEAVRDSMSQVIPAGYTQAARLLAQGTLADDVAQLRMPIAVASGNADSITTPLS
CQAVAQAAGVAWNDLGVAGHACPLEAPGPVNALLGLH

Download         Length: 834 bp

>T141064 NZ_CP059738:c2165407-2164904 [Pseudomonas sp. 29A]
ATGTGGCTTGCCCTCTCGGGGCGGTTCCGGGCGCGATGGAGCAAGGAGATTCACAGCGAATGGAAACGCAATCTATTGAA
GAACCGCACTGACCTGACCATGGAACAACTGGATCGTACGTCTGAATTGATGGACCGCGCGATCCCCGAAGCTTGCGTCT
GCGACTACGAAGAACTGGTCAACGGATTGTCATTGCCCGATCAGGATGACCGTCATGTACTGGCGGCAGCCATTCGCTGT
GGTGCAGGCGTCATCGTGACGTTCAACTTGAAAGACTTTCCCGATACGCAGCTCGCCCCTTTTGGTTTCGAAGCACAGCA
TCCCGATGAGTTCGTCGAAAACCTGTTCCATCTTAATTCGGCAGCAGTTGTCGCTGCCGCCCAAAAGCAGCGAAAACAAC
TGAAAACGCCAGCGATGGATGTCGAGTCGTTTTTGCGATTACTGCAACGACAAGGATTGACCCAGTCGGTCCAAGCGCTT
GAAGGTTATCGCGCCATTCTCTGA

Antitoxin


Download         Length: 277 a.a.        Molecular weight: 30317.70 Da        Isoelectric Point: 6.6550

>AT141064 WP_159593220.1 NZ_CP044549:c2525551-2524721 [Hydrogenophaga sp. BPS33]
MATEKTTDDRYTVPALMRGLQLLMLFNRDERELTGAEISRRLELPRASVFRMLQTLEQGGFVERVGDGAYYKLGLAVLRL
GFEFLASMELTEHGRPVIEALRDACGYSAHVVVRDGRDAVFIAKVAGRNALFHSIQVGARLPAHATVLGRLLLSDLDLDG
LRQLYPEPELPSYTPKTPSTVEQLKVLIDADRARGYGVSQGGFETGISTIAAPVFNDRGEVAAAVSITVPAQQVQPGELE
VLINQVREAADRLTARISHLPERGSWQNKPTEKKVA

Download         Length: 831 bp

>AT141064 NZ_CP059738:c2165956-2165489 [Pseudomonas sp. 29A]
ATGTCGATTGTTATTCATCCGCCGGTCACCCTCCCCGTAGAGCGCGAGATCAAAGCCGCCATCGAGGGCCAGCGTGCCTT
GGCCGCTTACCTCGCTACCCAATTCGAAACCCAGCACATACAGATCTTCGATGAGCAGAACGAAGCTCATCGTGTCGAGT
TGCCAACGTCGGCCTTGCGCCTGCTTGCTGACATTCTTGCAGCGCTGGCAGAGGGCAACGCCGTTAAAGTCGTGCCAGTA
CACGCCGAACTGACCACCCAGGAAGCCGCTGATCTGCTCAATGTCTCACGCCCGCACATGATTAAGCTGCTGGAAAGCGG
CGAGATTTCCTACCATAAAACCGGCAAGCACCGACGTGTGCGCTTTGCCGATCTGATGGATTATAAGACCCGGCGTGACA
GCGCCAGCGAGCAGGCAATGGCGCTGCTCGCGGAGCAGGCACAAGCATTAAGGACAGGATACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References