Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 122575..123269 Replicon plasmid pBbPL7HG1
Accession NZ_CP044544
Organism Bradyrhizobium betae strain PL7HG1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag F8237_RS35040 Protein ID WP_151650813.1
Coordinates 122850..123269 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag F8237_RS35035 Protein ID WP_151650812.1
Coordinates 122575..122853 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F8237_RS35015 118142..119092 - 951 WP_151650808.1 DUF1612 and helix-turn-helix domain-containing protein -
F8237_RS35020 119203..120846 + 1644 WP_151650809.1 Mu transposase C-terminal domain-containing protein -
F8237_RS35025 120827..121705 + 879 WP_162006441.1 TniB family NTP-binding protein -
F8237_RS35030 122154..122453 - 300 WP_151650811.1 prevent-host-death protein -
F8237_RS35035 122575..122853 + 279 WP_151650812.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
F8237_RS35040 122850..123269 + 420 WP_151650813.1 type II toxin-antitoxin system VapC family toxin Toxin
F8237_RS35045 123352..123585 + 234 WP_048758120.1 DUF433 domain-containing protein -
F8237_RS35050 123585..123953 + 369 WP_048758121.1 DUF5615 family PIN-like protein -
F8237_RS35055 123953..125137 + 1185 WP_151650814.1 site-specific integrase -
F8237_RS35060 125351..126553 + 1203 WP_151650834.1 plasmid partitioning protein RepA -
F8237_RS35065 126550..127572 + 1023 WP_151650815.1 plasmid partitioning protein RepB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..269307 269307


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(13-59)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15357.80 Da        Isoelectric Point: 4.9114

>T141059 WP_151650813.1 NZ_CP044544:122850-123269 [Bradyrhizobium betae]
MNVLLDTNVLSEVRRPAPDPKVLGWLDTIDEDRAFISVASIAELRRGIVLMDDGRRRAALTAWLAEDLPARFAGRILPID
PAIAERWGDLMAKARQNGFALSVMDGFFAATALAKELVLATRNTKDFVPLGLPVFNPWD

Download         Length: 420 bp

>T141059 NZ_CP059734:c1148618-1148328 [Thalassomonas viridans]
GTGTCACAATTGATCTGGTCTCCGCCAGCCCTGGCGGATGTTCAACGGATTTATCGTTTCCTGGCGCCGAAAGATCCAGC
TGCTGCCCGCCGAGCGGTCAAGGCGATACGGGCCGGTGTGAAAATTCTTGCTCACCAGCCGGAAGTTGGACGACCGGTGG
AAAATATGGAGCCGGCCTTTCGGGAGTGGCTGATCGATTTCGGTAGCACCGGTTATCTTGCATTGTATCGGCTTGCTGGT
GACACGGCTGTTATCCTGGCGGTACGGCACCAGAAAGAAGCGGGCTATTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10357.76 Da        Isoelectric Point: 7.3215

>AT141059 WP_151650812.1 NZ_CP044544:122575-122853 [Bradyrhizobium betae]
VTIPRKTPAHESDHWTVAGAKARLSEVIERAQTDPQIITRHGKPSVVMVSAEEWARKTVRKGTLAEFLMASPLRDADLDL
DRVRDQSRDLDL

Download         Length: 279 bp

>AT141059 NZ_CP059734:c1148878-1148606 [Thalassomonas viridans]
ATGGCAACATCAATAAAACTCGACGACGATCTGAAAAGCCGGATCCAGCACCTGGCCGAGCTACGGCATAGATCTGCTCA
CTGGATCATGCGTGAAGCGATCCGGGATTATGTGGAGCGGGAGGAAAAGCGGGAAGCATTTAAACAGGATGCCCTGAATG
CCTGGGAAGCATACCAGAATAACGGACTGCATCTAACGCTGGAAGAGGCTGATGCCTGGTTGGCCAAGCTTGAAGGCGGT
GAAGATGACGGAGTACCTGAGTGTCACAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References