Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-Phd |
Location | 82568..83235 | Replicon | chromosome |
Accession | NZ_CP044543 | ||
Organism | Bradyrhizobium betae strain PL7HG1 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | F8237_RS00350 | Protein ID | WP_151641875.1 |
Coordinates | 82825..83235 (+) | Length | 137 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | F8237_RS00345 | Protein ID | WP_151641874.1 |
Coordinates | 82568..82825 (+) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
F8237_RS00320 | 77918..78358 | + | 441 | WP_151641869.1 | response regulator | - |
F8237_RS00325 | 78355..79458 | + | 1104 | WP_151641870.1 | response regulator | - |
F8237_RS00330 | 79523..80203 | + | 681 | WP_151641871.1 | leucyl/phenylalanyl-tRNA--protein transferase | - |
F8237_RS00335 | 80285..81319 | - | 1035 | WP_162005818.1 | DUF2155 domain-containing protein | - |
F8237_RS00340 | 81526..82473 | + | 948 | WP_151641873.1 | alpha/beta hydrolase | - |
F8237_RS00345 | 82568..82825 | + | 258 | WP_151641874.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
F8237_RS00350 | 82825..83235 | + | 411 | WP_151641875.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
F8237_RS00355 | 83275..84240 | + | 966 | Protein_71 | Na+-dependent transporter | - |
F8237_RS00360 | 84575..86014 | + | 1440 | WP_151641876.1 | porin family protein | - |
F8237_RS00365 | 86080..87021 | - | 942 | WP_151641877.1 | GlxA family transcriptional regulator | - |
F8237_RS00370 | 87113..87799 | + | 687 | WP_151641878.1 | DJ-1/PfpI family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 15022.29 Da Isoelectric Point: 8.7358
>T141058 WP_151641875.1 NZ_CP044543:82825-83235 [Bradyrhizobium betae]
MFLLDTVTLSELRRTRRNPSVVAWMERQRTPDLFLSVVSIGEIERGIARQRAADPSFADALAAWLDRLLALYGAQILPFD
LQTARRWGTLSAALGNESADLMIAATALEHGLTVVTRNVSDFKPAGVRIVNPFEGK
MFLLDTVTLSELRRTRRNPSVVAWMERQRTPDLFLSVVSIGEIERGIARQRAADPSFADALAAWLDRLLALYGAQILPFD
LQTARRWGTLSAALGNESADLMIAATALEHGLTVVTRNVSDFKPAGVRIVNPFEGK
Download Length: 411 bp
>T141058 NZ_CP059733:c5448653-5448366 [Thalassomonas viridans]
ATGACCTATAGATTAAAATTTTTGCCTGTAGCAAAAAAAGAGTGGGATAAACTGGCGCAACCTATCAAGAATCAATTTAA
GAAAAAGCTTGCCCAAAGGCTCGAAAATCCGCATGTACCGGCTGCAAGGCTACGCGGCTATGACTTTGTTTATAAAATAA
AATTAAAAACTGCAGGCTATCGTTTAGCTTATGAAGTCATAGATGACGAAGTTGTTGTTTATGTGCTAGCGGTTGGTAAG
CGTGAAAAAAATGCCGTATACAAAAAATTAGTATCACGTATTGAATAA
ATGACCTATAGATTAAAATTTTTGCCTGTAGCAAAAAAAGAGTGGGATAAACTGGCGCAACCTATCAAGAATCAATTTAA
GAAAAAGCTTGCCCAAAGGCTCGAAAATCCGCATGTACCGGCTGCAAGGCTACGCGGCTATGACTTTGTTTATAAAATAA
AATTAAAAACTGCAGGCTATCGTTTAGCTTATGAAGTCATAGATGACGAAGTTGTTGTTTATGTGCTAGCGGTTGGTAAG
CGTGAAAAAAATGCCGTATACAAAAAATTAGTATCACGTATTGAATAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9684.00 Da Isoelectric Point: 8.9140
>AT141058 WP_151641874.1 NZ_CP044543:82568-82825 [Bradyrhizobium betae]
MSKRVWSVQDAKNRFSEVVNAAQRAPQTVTRHGKPTVVILNAAEFERLQELQRARAPSLSDLLLEMPQDDEEFPRARIAN
RDIGL
MSKRVWSVQDAKNRFSEVVNAAQRAPQTVTRHGKPTVVILNAAEFERLQELQRARAPSLSDLLLEMPQDDEEFPRARIAN
RDIGL
Download Length: 258 bp
>AT141058 NZ_CP059733:c5448894-5448643 [Thalassomonas viridans]
ATGAGACAAGTTTTAGCTGATTGTTCAGCAAGCATTTCCGAGTTAAAGAAAAACCCGACAGCACTTATTAATGAAGCCGA
TGGTGCGGCTATTGCTATTTTGAATCACAACAAACCCGCAGCTTATCTGGTACCTGCTGAAACATATGAATGGCTTATGG
ATATGCTCGAAGATTATGAATTGGGTAAAATCGTTGAAAGCAGGCGTTCAGATTTATCAGAAGCTGTGGAAGTTAGCCTG
GATGACCTATAG
ATGAGACAAGTTTTAGCTGATTGTTCAGCAAGCATTTCCGAGTTAAAGAAAAACCCGACAGCACTTATTAATGAAGCCGA
TGGTGCGGCTATTGCTATTTTGAATCACAACAAACCCGCAGCTTATCTGGTACCTGCTGAAACATATGAATGGCTTATGG
ATATGCTCGAAGATTATGAATTGGGTAAAATCGTTGAAAGCAGGCGTTCAGATTTATCAGAAGCTGTGGAAGTTAGCCTG
GATGACCTATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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