Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 82568..83235 Replicon chromosome
Accession NZ_CP044543
Organism Bradyrhizobium betae strain PL7HG1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag F8237_RS00350 Protein ID WP_151641875.1
Coordinates 82825..83235 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag F8237_RS00345 Protein ID WP_151641874.1
Coordinates 82568..82825 (+) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F8237_RS00320 77918..78358 + 441 WP_151641869.1 response regulator -
F8237_RS00325 78355..79458 + 1104 WP_151641870.1 response regulator -
F8237_RS00330 79523..80203 + 681 WP_151641871.1 leucyl/phenylalanyl-tRNA--protein transferase -
F8237_RS00335 80285..81319 - 1035 WP_162005818.1 DUF2155 domain-containing protein -
F8237_RS00340 81526..82473 + 948 WP_151641873.1 alpha/beta hydrolase -
F8237_RS00345 82568..82825 + 258 WP_151641874.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
F8237_RS00350 82825..83235 + 411 WP_151641875.1 type II toxin-antitoxin system VapC family toxin Toxin
F8237_RS00355 83275..84240 + 966 Protein_71 Na+-dependent transporter -
F8237_RS00360 84575..86014 + 1440 WP_151641876.1 porin family protein -
F8237_RS00365 86080..87021 - 942 WP_151641877.1 GlxA family transcriptional regulator -
F8237_RS00370 87113..87799 + 687 WP_151641878.1 DJ-1/PfpI family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-118)

Antitoxin

(4-56)


Sequences


Toxin        


Download         Length: 137 a.a.        Molecular weight: 15022.29 Da        Isoelectric Point: 8.7358

>T141058 WP_151641875.1 NZ_CP044543:82825-83235 [Bradyrhizobium betae]
MFLLDTVTLSELRRTRRNPSVVAWMERQRTPDLFLSVVSIGEIERGIARQRAADPSFADALAAWLDRLLALYGAQILPFD
LQTARRWGTLSAALGNESADLMIAATALEHGLTVVTRNVSDFKPAGVRIVNPFEGK

Download         Length: 411 bp

>T141058 NZ_CP059733:c5448653-5448366 [Thalassomonas viridans]
ATGACCTATAGATTAAAATTTTTGCCTGTAGCAAAAAAAGAGTGGGATAAACTGGCGCAACCTATCAAGAATCAATTTAA
GAAAAAGCTTGCCCAAAGGCTCGAAAATCCGCATGTACCGGCTGCAAGGCTACGCGGCTATGACTTTGTTTATAAAATAA
AATTAAAAACTGCAGGCTATCGTTTAGCTTATGAAGTCATAGATGACGAAGTTGTTGTTTATGTGCTAGCGGTTGGTAAG
CGTGAAAAAAATGCCGTATACAAAAAATTAGTATCACGTATTGAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9684.00 Da        Isoelectric Point: 8.9140

>AT141058 WP_151641874.1 NZ_CP044543:82568-82825 [Bradyrhizobium betae]
MSKRVWSVQDAKNRFSEVVNAAQRAPQTVTRHGKPTVVILNAAEFERLQELQRARAPSLSDLLLEMPQDDEEFPRARIAN
RDIGL

Download         Length: 258 bp

>AT141058 NZ_CP059733:c5448894-5448643 [Thalassomonas viridans]
ATGAGACAAGTTTTAGCTGATTGTTCAGCAAGCATTTCCGAGTTAAAGAAAAACCCGACAGCACTTATTAATGAAGCCGA
TGGTGCGGCTATTGCTATTTTGAATCACAACAAACCCGCAGCTTATCTGGTACCTGCTGAAACATATGAATGGCTTATGG
ATATGCTCGAAGATTATGAATTGGGTAAAATCGTTGAAAGCAGGCGTTCAGATTTATCAGAAGCTGTGGAAGTTAGCCTG
GATGACCTATAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References