Detailed information of TA system TA141037

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3585590..3586231
• Replicon: chromosome
• Accession: NZ_CP044519
• Organism: Acinetobacter baumannii strain 29FS20

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: F7R60_RS17110
• Protein ID: WP_000607096.1
• Coordinates: 3585590..3585979 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: F7R60_RS17115
• Protein ID: WP_011860336.1
• Coordinates: 3585986..3586231 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F7R60_RS17095	3580708..3582903	-	2196	WP_001158905.1	TRAP transporter large permease subunit	-
F7R60_RS17100	3583091..3583657	-	567	WP_000651536.1	rhombosortase	-
F7R60_RS17105	3583735..3584820	-	1086	WP_000049106.1	hypothetical protein	-
F7R60_RS17110	3585590..3585979	-	390	WP_000607096.1	hypothetical protein	Toxin
F7R60_RS17115	3585986..3586231	-	246	WP_011860336.1	succinate dehydrogenase assembly factor 2	Antitoxin
F7R60_RS17120	3586431..3587603	+	1173	WP_001190543.1	acyl-CoA dehydrogenase family protein	-
F7R60_RS17125	3587652..3589142	-	1491	WP_000415137.1	NAD(P)/FAD-dependent oxidoreductase	-
F7R60_RS17130	3589324..3589701	-	378	WP_001216380.1	50S ribosomal protein L17	-
F7R60_RS17135	3589720..3590727	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15583.80 Da
• Isoelectric Point: 10.4637

>T141037 WP_000607096.1 NZ_CP044519:c3585979-3585590 [Acinetobacter baumannii]
MINHSNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Nucleotide

• Length: 390 bp

>T141037 NZ_CP059723:c713279-712992 [Escherichia coli]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9842.27 Da
• Isoelectric Point: 4.9001

>AT141037 WP_011860336.1 NZ_CP044519:c3586231-3585986 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT141037 NZ_CP059723:c713518-713279 [Escherichia coli]
ATGGGTAGCATTAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGTGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGGCTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA