Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3421662..3422303 Replicon chromosome
Accession NZ_CP044517
Organism Acinetobacter baumannii strain 31FS3-2

Toxin (Protein)


Gene name cptA Uniprot ID A0A7Z1WP95
Locus tag F7R97_RS16260 Protein ID WP_002061280.1
Coordinates 3421662..3422051 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag F7R97_RS16265 Protein ID WP_011860336.1
Coordinates 3422058..3422303 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F7R97_RS16245 3416780..3418975 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
F7R97_RS16250 3419163..3419729 - 567 WP_000651536.1 rhombosortase -
F7R97_RS16255 3419807..3420892 - 1086 WP_000049106.1 hypothetical protein -
F7R97_RS16260 3421662..3422051 - 390 WP_002061280.1 hypothetical protein Toxin
F7R97_RS16265 3422058..3422303 - 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
F7R97_RS16270 3422503..3423675 + 1173 WP_140951711.1 acyl-CoA dehydrogenase family protein -
F7R97_RS16275 3423724..3425214 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
F7R97_RS16280 3425396..3425773 - 378 WP_001216380.1 50S ribosomal protein L17 -
F7R97_RS16285 3425792..3426799 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15635.96 Da        Isoelectric Point: 10.4623

>T141034 WP_002061280.1 NZ_CP044517:c3422051-3421662 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T141034 NZ_CP059723:c363483-363376 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT141034 WP_011860336.1 NZ_CP044517:c3422303-3422058 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT141034 NZ_CP059723:363530-363596 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z1WP95

Antitoxin

Source ID Structure

References