Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1188946..1189459 Replicon chromosome
Accession NZ_CP044507
Organism Chryseobacterium sp. strain SNU WT7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag F7R58_RS05625 Protein ID WP_158063964.1
Coordinates 1189202..1189459 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag F7R58_RS05620 Protein ID WP_158063963.1
Coordinates 1188946..1189200 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F7R58_RS05600 1184339..1184701 + 363 WP_158063959.1 BlaI/MecI/CopY family transcriptional regulator -
F7R58_RS05605 1184701..1186617 + 1917 WP_158063960.1 M56 family metallopeptidase -
F7R58_RS05610 1187005..1187658 - 654 WP_158063961.1 fructose-6-phosphate aldolase -
F7R58_RS05615 1188064..1188756 + 693 WP_158063962.1 dipeptidase PepE -
F7R58_RS05620 1188946..1189200 + 255 WP_158063963.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F7R58_RS05625 1189202..1189459 + 258 WP_158063964.1 Txe/YoeB family addiction module toxin Toxin
F7R58_RS05630 1189785..1190198 - 414 WP_158063965.1 hypothetical protein -
F7R58_RS05635 1190246..1191148 - 903 WP_158063966.1 exopolyphosphatase -
F7R58_RS05640 1191160..1193223 - 2064 WP_158063967.1 polyphosphate kinase 1 -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-84)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 86 a.a.        Molecular weight: 10535.06 Da        Isoelectric Point: 8.4421

>T141025 WP_158063964.1 NZ_CP044507:1189202-1189459 [Chryseobacterium sp.]
MKYIFVDESCEDYLYWQKTDKKKLKRINDLLKDISRNPFEGIGKPEPLKHKYSGFWSRRIDEEHRLIYKYQDDDILIAKC
RFHYD

Download         Length: 258 bp

>T141025 NZ_CP059711:4057798-4058175 [Enterobacter hormaechei]
ATGCAAACACAACCTGTTCCTCCGAAACGGGAGGTTTCGCCACGCCCGTCACCCGTGGCGATCTGGCAGCGCCTCCTGAG
TCACCTGCTGGACCGTCACTACGGTCTGACGCTCAACGACACGCCATTTGGCAAAGATGGTGTGATCCAAGAGCATATCG
ATGCCGGTATCTCACTGTGCGACGCGGTGAATTTCATCGTGGAGAAATACGACCTGGTACGCACTGATCGTCGCGGTTTT
AACGCGGAAACTCAGTCGCCGCTTCTCACCAGTATCGATATTCTCCGCGCCCGCAAAGCCACCGGGCTGATGACCCGTCA
TAGCTACAGGGCCGTTACCGACATCACCACCGGCAAATACCGTGAGGTGCAACCATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9579.88 Da        Isoelectric Point: 5.1351

>AT141025 WP_158063963.1 NZ_CP044507:1188946-1189200 [Chryseobacterium sp.]
MLIASVSDFRKDIKSYLDRVAKNFETLIINRGKDSAIVVMSLDEYNSLMATNYELSSRRNELRLDAAIEKLKSGNSFSKD
LTEE

Download         Length: 255 bp

>AT141025 NZ_CP059711:4057422-4057748 [Enterobacter hormaechei]
ATCGCCGCCCCTTGGTGGGGGCTTAAACGCGATATCACCCCCTGTTTTGGCGCACGTCTGGTGCAGGAGGGCAACCGGCT
GCATTACCTGAACGACCGCGCCAGCATCACCGGCACCTTCAGCGACGCGGATTTACGCCATCTCGACCAGGCATTCCCGC
TACTGCTGAAGCAACTGGAGCTGATGCTGCTTTCCGGTGAGCTGAATCCCCGTCATCAGCACTGCGTCACGCTGTATGCA
AAAGGGCTGATATGCGAGGCCGACAGCCTCGGCTCGCACGGGTACGTCTATCTCGCAATTTACCCGACACCTGCAACAAC
AGAATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References