Detailed information of TA system TA141003

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 88..655
• Replicon: plasmid pHZE33-1-8
• Accession: NZ_CP044482
• Organism: Acinetobacter schindleri strain HZE33-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: N9QF31
• Locus tag: FSC12_RS16035
• Protein ID: WP_005098405.1
• Coordinates: 88..369 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FSC12_RS16040
• Protein ID: WP_107010145.1
• Coordinates: 362..655 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FSC12_RS16030	1..5330	-	5330	WP_107010146.1	hypothetical protein	-
FSC12_RS16035	88..369	-	282	WP_005098405.1	type II toxin-antitoxin system YafQ family toxin	Toxin
FSC12_RS16040	362..655	-	294	WP_107010145.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
FSC12_RS16045	799..1299	-	501	WP_005098403.1	hypothetical protein	-
FSC12_RS16050	1296..2225	-	930	WP_163169842.1	MobA/MobL family protein	-
FSC12_RS16150	2225..2380	-	156	WP_171521814.1	hypothetical protein	-
FSC12_RS16055	2660..3073	+	414	WP_107010148.1	conjugal transfer protein TraD	-
FSC12_RS16060	3077..3757	+	681	WP_107010147.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..5330	5330

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-92)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-90)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10693.41 Da
• Isoelectric Point: 6.8520

>T141003 WP_005098405.1 NZ_CP044482:c369-88 [Acinetobacter schindleri]
MAKRKIIVTSSFKRDIKRRYLDLVTAEWAEVLDCLVANSPLPEKYLDHPLKGGAEFKNCRDCHVKPDLVLIYRLVGDDVL
ELHQLDSHSEIFG

Nucleotide

• Length: 282 bp

>T141003 NZ_CP059591:1541442-1542365 [Xanthomonas oryzae pv. oryzae]
ATGAACGAACCTGACAAGAGCAGGCGCACTGTTGCCGCGTCGGTTCGCGCCCGGCTGCTCAACAAGGCCCGCGCCGAAAG
ACTCGACTTCAACCTGCTGCTGACCCGCTACGCGCTGGAGCGCGTCCTTTACCGCCTGAGCGTTTCGGAGCAGCAGGGTC
AATTCTTGCTCAAAGGTGCGCTGCTGTTCGACATCTGGTTCGACATACCGCATCGCCCGACGCACGATGCCGACCTGCTG
GGCTTCGGCTCCACTGAGATCCCACATCTGGAAGACCTGTTCCGCAGAATCAGTCAAATCGCCAGCGATGACGGCATCGT
GTTTCAGGCCGACAGCGTGAAGGCCGCCGAAATCCGCAAGGAGGCCAACTACGCGGGCGTCCGTGTGACGATGATCGGCC
TGCTCGATGGCGCGCGCTGCACGGTGCAGATCGACATCGGTTTCGGCGACGCCGTGACGCCCGGCCCGGACAACGTGCAG
TACCCAGTCATCCTCGACGGCATGCCGCAGCCGCAACTGCGGGTCTATCCCCGCTACACCGTGGTCGCCGAAAAGCTGGA
AGCGATGGTCAAGCTCGGCATCCTCAACAGCCGGATGAAGGACTACTTCGACCTCTGGGTTCTCGCCGGACATTCCGACT
TCGACGGTGCGGTGCTGGCCACGGCCATTCGCGCCACGTTCGAGTGCAGGGGTACGGCCATCCCACCCGGCGCGCCGCTG
GGCCTCACCGATGAGTTCGGCCTGGACGAGCAGAAGACAAAGCAGTGGCAGGCGTTCCTGCGCAAGAACACCTTGGAGCC
GATGCCGCTGACCACGGTGATCGAAGCGCTGCGCGAATTCGTGCTGCCCGTGCTGGCCGCGCTCGCGGCAGGCGAAGGTT
TCGACCGCCAGTGGCGCGCGGGCGCGGGATGGGATGCGGCCTGA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10957.53 Da
• Isoelectric Point: 4.4345

>AT141003 WP_107010145.1 NZ_CP044482:c655-362 [Acinetobacter schindleri]
MSAVNFNMRLEAELKEKVTPILEDYGLTMPQAFKLFLNQIVKTKTIPLSFDYARETALTPKAAAKLLHSLKEIENGEYTE
YETVEEAIQAMSEEANG

Nucleotide

• Length: 294 bp

>AT141003 NZ_CP059591:1540846-1541445 [Xanthomonas oryzae pv. oryzae]
ATGGACACGACCGTCGACAAGCTGCTGGAGCTGGTGCGTACGCGGGGACTTCTGCGCCCGCACGATCTGGCCCCACTGGG
CATCCCACGGGTGGCCCTGACGCGGGCCGTTCGGCGCGGGCAACTGGAGCGCGTCGGGCGCGGCCTGTACGGCCTGGTGG
CGCGTCCGGTGTCGGCCCACGGCACGCTGGCCGAAGTCGCGCGCCGCGTGCCCAAGGGCGTGGTCTGCCTGCTGTCGGCG
CTGCGCGTCCACGACCTGACGACCCAGGCCCCGTTCGAGGTGTGGCTGGCCATCGACAACAAGGCCGCTGCCCCGAAGCT
GGACTACCCGCCGCTACGTCTCGTGCGCTTCTCCGGGCCGGCGCTGAGCGAGGGCGTCGAGGAACACGTTGTCGATGGTG
TGCCCGTCCACGTGACCAGCGTCGCCAAGACCGTGGCCGACTGCTTCAAGTACCGCAACAAGATCGGCATCGACGTGGCG
CTGGAAGCGCTGCGCGAGGCGTGGGTTGCCCGGCGCATGACCAGCGACGAGATCTGGCACTACGCCAAGATCGACCGCGT
CGCCAACGTGATGCGTCCCTATCTGGAGAGCCTGGCATGA

Structures

Toxin

• AlphaFold DB: N9QF31