Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 82810..83952 Replicon plasmid pB18-1
Accession NZ_CP044456
Organism Acinetobacter indicus strain B18

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FSC09_RS15070 Protein ID WP_163146385.1
Coordinates 83188..83952 (+) Length 255 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FSC09_RS15065 Protein ID WP_163146384.1
Coordinates 82810..83178 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FSC09_RS15040 78362..79381 + 1020 WP_163146380.1 hypothetical protein -
FSC09_RS15045 79448..79867 + 420 WP_163146381.1 acyl-CoA thioesterase -
FSC09_RS15050 79900..80832 + 933 WP_163146382.1 DMT family transporter -
FSC09_RS15055 80825..81562 + 738 WP_163146383.1 acetoacetyl-CoA reductase -
FSC09_RS15060 81733..82664 + 932 Protein_48 IS5 family transposase -
FSC09_RS15065 82810..83178 + 369 WP_163146384.1 XRE family transcriptional regulator Antitoxin
FSC09_RS15070 83188..83952 + 765 WP_163146385.1 RES family NAD+ phosphorylase Toxin
FSC09_RS15075 84009..84392 - 384 WP_163146386.1 hypothetical protein -
FSC09_RS15080 84516..85418 + 903 WP_163146387.1 hypothetical protein -
FSC09_RS15085 85493..85630 - 138 WP_163146388.1 hypothetical protein -
FSC09_RS15090 85649..86323 - 675 WP_163146389.1 hypothetical protein -
FSC09_RS15095 86451..87044 + 594 WP_163146390.1 hypothetical protein -
FSC09_RS15100 87084..88514 + 1431 WP_163146391.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..274859 274859


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(71-207)

Antitoxin

Cro/C1-type helix-turn-helix domain

(17-55)


Sequences

Toxin        


Download         Length: 255 a.a.        Molecular weight: 28860.46 Da        Isoelectric Point: 4.8115

>T140997 WP_163146385.1 NZ_CP044456:83188-83952 [Acinetobacter indicus]
MKATDSIWKACRGEEQIVPVSGVLFRMVKKLEQIATWQIVENLGEQAELEDLIEEKISAVSSLPKEDELHILLKAPFQYP
PLEWGSRFGRTHEPSIFYGGCSVDATLAELAYYRFVYLQNIDTNSGESMQSQHLMFSVGYQSEKGIRLQDPPFDQHHDLI
AHPSNYSRAQQLGAEMRVAEVEVFEYPSSRAADHAPCVGIFTPGNFTQNYPLSQEEWLSELTRDTVTFKSMGSRLVKTYS
ISDFFHNGEFPRPA

Download         Length: 765 bp

>T140997 NZ_CP059590:c2104875-2104594 [Xanthomonas oryzae pv. oryzae]
GTGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCACATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCGGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13318.50 Da        Isoelectric Point: 10.2156

>AT140997 WP_163146384.1 NZ_CP044456:82810-83178 [Acinetobacter indicus]
MSDVVERPKVDRKAVLSKALLNAADQLKINQADLAEVIGVHRTAISKLKKKPDLDPDSKAGELAVLFIRLYRGVYALNGG
NQDWMLRFLNSPNKATGGVPAQQIKTVQGLVHVVQYLDAMPG

Download         Length: 369 bp

>AT140997 NZ_CP059590:c2104576-2104286 [Xanthomonas oryzae pv. oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAATGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References