Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2346967..2347495 Replicon chromosome
Accession NZ_CP044455
Organism Acinetobacter indicus strain B18

Toxin (Protein)


Gene name relE Uniprot ID N9N871
Locus tag FSC09_RS11395 Protein ID WP_000221358.1
Coordinates 2347202..2347495 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID N9B5Q7
Locus tag FSC09_RS11390 Protein ID WP_000246756.1
Coordinates 2346967..2347212 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FSC09_RS11360 2342549..2343358 + 810 WP_016659852.1 cytochrome c biogenesis protein CcsA -
FSC09_RS11365 2343554..2344108 - 555 WP_127798694.1 hypothetical protein -
FSC09_RS11370 2344148..2344501 - 354 Protein_2205 transposase family protein -
FSC09_RS11375 2344857..2345276 - 420 WP_039255596.1 PPC domain-containing protein -
FSC09_RS11380 2345626..2346566 + 941 Protein_2207 IS5 family transposase -
FSC09_RS11385 2346578..2346808 - 231 WP_127800942.1 hypothetical protein -
FSC09_RS11390 2346967..2347212 + 246 WP_000246756.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FSC09_RS11395 2347202..2347495 + 294 WP_000221358.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FSC09_RS11400 2347573..2348898 - 1326 WP_127801714.1 ISNCY family transposase -
FSC09_RS11405 2349187..2350392 + 1206 WP_171524614.1 alpha/beta fold hydrolase -
FSC09_RS11410 2350490..2351263 + 774 WP_163146333.1 glucose 1-dehydrogenase -
FSC09_RS11415 2351530..2352453 + 924 WP_127800843.1 tRNA-dihydrouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 2344148..2348910 4762


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-71)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11292.52 Da        Isoelectric Point: 10.4753

>T140996 WP_000221358.1 NZ_CP044455:2347202-2347495 [Acinetobacter indicus]
MTYKLLRHKDFTAEWEKLPVAIRDQFKKKLAKVIEQPHIPKNMLRGDLAGCYKIKLLKAGVRLVYQVKDDQVVILLITVG
KRADSIVYDEAKKRIKD

Download         Length: 294 bp

>T140996 NZ_CP059590:1254711-1255364 [Xanthomonas oryzae pv. oryzae]
ATGGCTGAGCATTACTCCAAACTCAACCCAAAGAACGCCCTGATCTGGCGCATCACCCACCGGGGCAATCTGCCGTGGAT
TCTGGACAACGGTCTGCACTGTGGTAATGCCGCTGTGCAGAGTTCGAGTTGGGTGAGCATCGGCAACCCAGAACTGATCG
ACAAGCGCTCCAGTCATGCTGTACCGCGTCCACCGGGCGGCTTCTTAAACGATTACGTGCCGTTCTACTTCACTCCGTTT
TCGCCGATGCTGCACAACATCCATACCGGCTGGCGTGGAATCCCAAGGCGGCCTAACGAAGACATCGTCATCCTTGTTTC
CAGCTTGCATCATGTCGCCGAACGCCGATGGCCGTTTCTGTTTACTGACAGCCACGCCTCCTGCCAGTTGGCGAGCTTCT
ATTCCGATTTATCTGATCTCGACAAGATCGACTGGCCGTTGCTCCAAGCACGCGATTTCCGGCGCGACCCAGACGACCCA
GCCAAGTTCGAGCGCTATCAGGCCGAGGCCCTGATTCACCGACACTTGCCGCTTGATGGCCTGCGCGGCATTGTGTGTCA
TACGGATGGTTTGAAACAGACCATCGAGCGGCAACTCCAAGAGCGAAACCTGAAATTGCCGGTTCATACCCGCACCGATT
GGTATTTCCGATGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9235.61 Da        Isoelectric Point: 4.3142

>AT140996 WP_000246756.1 NZ_CP044455:2346967-2347212 [Acinetobacter indicus]
MATVNFRVDEALKEKSYSILKEQGIAPTDFFTSILEYVATTGKLPVKKALLSEEDEELLALVRKRINDPKEMFEEVTLDD
L

Download         Length: 246 bp

>AT140996 NZ_CP059590:1255361-1256431 [Xanthomonas oryzae pv. oryzae]
ATGATCACGTTTACACAAGGCAATCTACTGGAGTCTGGCGCAGAGGCGCTGGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAAGGAGAACTTCCTCCGATATGCCGCCGCCTGCAAAGACAACC
AAGTGCGCATTGGCAAAATTTTCGTCACCGAAGTCAACGAACTGGACGGGCCACGCTGGATCATCAATTTTCCGACCAAA
CAGCACTGGCGTGGCGATTCCCGCATCGAATGGATCACTGAAGGATTGCAGGACTTGCACCTTTTTCTGATCGAGAACAA
AGTCAAATCCATTGCCATCCCGCCACTGGGCGCGGGCAATGGAGGATTGGACTGGGCCGAGGTGCGCCCACTGATCGAAG
AAGTACTAGCAGGTTTGGATACAGACATCCTCGTGTTCGAGCCTACCTTAAAGTATCAGAACGTTGCCAAGCGCTCCGGC
GTGGAAAAATTGACCCCGGCACGCGCCTTGATTGCCGAGCTGGTACGTCGTTACTGGGTGCTAGGTATGGAATGCGGCCT
GTTGGAAATCCAGAAACTGGCGTGGTTCCTTGAACGCAACATCGAGCGAGCGGGCTTGCCTGAGCTTGATTTGCGCTTTT
CAGCACACAAGTACGGCCCTTATGCCGACCGTCTACGCCATCTTCTGAACGGGCTGGACGGAAGCTACCTGCATTGTGAC
AAACGGATCAGCGACGCCGACCCGCTGGACGTGATCTGGTTCGACGACAATCGCAAAAGCTTCGTACAGACCTACCTAAA
GAGCGAGGCGAAACAGTACATTCCAGCACTGGAAGCTACTGCCGCCTTGATCGATGGTTTTGAATCTCCTTTTGGCATGG
AGTTGTTGGCGACAGTTGACTGGCTGATTGTGCGGGAAGGTATCTCTGCGCAAGTTGCTGACGTGCGTGAAGGCATACGC
CACTGGCCAGGTGGTCAGGAGGCAGCGGCGCGAAAGGACAGACTGTTCGATGACCGCGCCTTGGGGATCGCGCTGAAACG
ACTGGCATCAGGTGCAATCGCAGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6A1RKP4

Antitoxin

Source ID Structure
AlphaFold DB N9B5Q7

References