140993

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 151..10430 Replicon plasmid pMMS9-2-4
Accession NZ_CP044454
Organism Acinetobacter indicus strain MMS9-2

Toxin (Protein)


Gene name brnT Uniprot ID A0A3G6Z3M6
Locus tag FSC05_RS15130 Protein ID WP_000438826.1
Coordinates 10430..164 (+) Length -3421.6666666667 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag FSC05_RS15135 Protein ID WP_163143636.1
Coordinates 151..465 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FSC05_RS15135 151..465 + 315 WP_163143636.1 BrnA antitoxin family protein Antitoxin
FSC05_RS15140 882..1271 + 390 WP_163143639.1 helix-turn-helix domain-containing protein -
FSC05_RS15145 1281..2084 + 804 WP_163143642.1 Abi family protein -
FSC05_RS15150 2260..2691 - 432 WP_163143646.1 hypothetical protein -
FSC05_RS15155 2709..2975 - 267 WP_006581723.1 hypothetical protein -
FSC05_RS15160 3185..4621 + 1437 WP_163143648.1 MobA/MobL family protein -
FSC05_RS15165 4723..4944 + 222 WP_163143651.1 hypothetical protein -
FSC05_RS15170 5147..6076 + 930 WP_004896921.1 replication initiation protein RepM -
FSC05_RS15175 6143..6685 + 543 WP_004896925.1 plasmid replication DNA-binding protein -
FSC05_RS15180 6820..8757 + 1938 WP_163143654.1 ATP-binding cassette domain-containing protein -
FSC05_RS15185 8927..9664 + 738 WP_163143657.1 SDR family NAD(P)-dependent oxidoreductase -
FSC05_RS15190 9737..10006 - 270 Protein_12 molecular chaperone DnaK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..10553 10553


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-96)


Sequences

Toxin        


Download         Length: -3421.6666666667 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T140993 WP_000438826.1 NZ_CP044454:10430-164 [Acinetobacter indicus]

Download         Length: -10265 bp

>T140993 NZ_CP059589:c4683659-4683525 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12266.92 Da        Isoelectric Point: 8.4842

>AT140993 WP_163143636.1 NZ_CP044454:151-465 [Acinetobacter indicus]
MSMVRYSRKELNEKFSEKQDAEIQRLLAKGTVPDDQLDLSDIPEITDWSNAVRHNQFYRPVKQQTSIRLDADVLAWFKAQ
GKGYQTRMNEILRDAMLKELKNHQ

Download         Length: 315 bp

>AT140993 NZ_CP059589:c4683875-4683723 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G6Z3M6

Antitoxin

Source ID Structure

References