Detailed information of TA system TA140990

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): NpoTA/ParE(toxin)
• Location: 1462928..1464043
• Replicon: chromosome
• Accession: NZ_CP044450
• Organism: Acinetobacter indicus strain MMS9-2

Toxin (Protein)

• Gene name: NpoT
• Uniprot ID: V2U6R6
• Locus tag: FSC05_RS06995
• Protein ID: WP_016658124.1
• Coordinates: 1462928..1463092 (-)
• Length: 55 a.a.

Antitoxin (Protein)

• Gene name: NpoA
• Uniprot ID: -
• Locus tag: FSC05_RS07000
• Protein ID: WP_005178053.1
• Coordinates: 1463174..1464043 (-)
• Length: 290 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FSC05_RS06980	1458909..1459931	+	1023	WP_127801679.1	ferredoxin reductase	-
FSC05_RS06985	1459955..1461112	+	1158	WP_171521850.1	fatty acid desaturase	-
FSC05_RS06990	1461411..1462829	+	1419	WP_127801681.1	iron-containing redox enzyme family protein	-
FSC05_RS06995	1462928..1463092	-	165	WP_016658124.1	hypothetical protein	Toxin
FSC05_RS07000	1463174..1464043	-	870	WP_005178053.1	SDR family oxidoreductase	Antitoxin
FSC05_RS07005	1464146..1464385	-	240	WP_104471337.1	DUF2171 domain-containing protein	-
FSC05_RS07010	1465044..1466285	+	1242	WP_127801682.1	MFS transporter	-
FSC05_RS07015	1466725..1467066	+	342	WP_127801683.1	KGG domain-containing protein	-
FSC05_RS07020	1467255..1467704	-	450	WP_127801684.1	cyanase	-
FSC05_RS07025	1467998..1468807	+	810	WP_127801685.1	formate/nitrite transporter family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 55 a.a.
• Molecular weight: 6182.76 Da
• Isoelectric Point: 10.1466

>T140990 WP_016658124.1 NZ_CP044450:c1463092-1462928 [Acinetobacter indicus]
MSRGDKSAYTDKQKRQARHIIESEKERGHSEEEAERIGWSTVNKQDGGGKKKSH

Nucleotide

• Length: 165 bp

>T140990 NZ_CP059589:336356-336637 [Xanthomonas oryzae pv. oryzae]
GTGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCACATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCGGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 290 a.a.
• Molecular weight: 31879.96 Da
• Isoelectric Point: 4.8531

>AT140990 WP_005178053.1 NZ_CP044450:c1464043-1463174 [Acinetobacter indicus]
MNHYPDSPSPQEKQEHQPGVQYKMTPEPEIIKSNYQGSQKLKDKVALITGGDSGIGRSVAVLFAREGANIIIPYLEEDQD
AQDTKRLVEQEGRQCLLIQCDLRQHAAVQQMVDLALQQFPHINILVNNAAVQYPQKTIEDINPEQLHKTFETNLYPLFYV
TQLLIPQMQAGDSIINTTSITSYQGHNELIDYASTKGAITAFTRSLSTNLLKNKTGIRVNGVAPGPIWTPLIPSSFDEEQ
LKGFGEDTPMGRMGQPSEVAPAYLFLASDEASYISGQVIHVNGGTIVNG

Nucleotide

• Length: 870 bp

>AT140990 NZ_CP059589:336655-336945 [Xanthomonas oryzae pv. oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAATGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Structures

Toxin

• AlphaFold DB: V2U6R6