Detailed information of TA system TA140988

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 2758067..2758691
• Replicon: chromosome
• Accession: NZ_CP044445
• Organism: Acinetobacter indicus strain CMG3-2

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: N9KY14
• Locus tag: FSC02_RS13175
• Protein ID: WP_005180237.1
• Coordinates: 2758067..2758459 (-)
• Length: 131 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: FSC02_RS13180
• Protein ID: WP_171065118.1
• Coordinates: 2758446..2758691 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FSC02_RS13150	2753169..2753330	+	162	Protein_2537	EamA/RhaT family transporter	-
FSC02_RS13155	2753392..2755668	-	2277	WP_127799343.1	TRAP transporter large permease subunit	-
FSC02_RS13160	2755849..2756421	-	573	WP_127799341.1	rhombosortase	-
FSC02_RS13165	2756477..2757550	-	1074	WP_016658537.1	hypothetical protein	-
FSC02_RS13170	2757740..2757919	+	180	WP_127801044.1	hypothetical protein	-
FSC02_RS13175	2758067..2758459	-	393	WP_005180237.1	hypothetical protein	Toxin
FSC02_RS13180	2758446..2758691	-	246	WP_171065118.1	succinate dehydrogenase assembly factor 2	Antitoxin
FSC02_RS13185	2758887..2760059	+	1173	WP_127801045.1	acyl-CoA dehydrogenase family protein	-
FSC02_RS13190	2760147..2761637	-	1491	WP_127801046.1	NAD(P)/FAD-dependent oxidoreductase	-
FSC02_RS13195	2761836..2762201	-	366	WP_004754212.1	50S ribosomal protein L17	-
FSC02_RS13200	2762221..2763228	-	1008	WP_005180245.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2752397..2753116	719

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 131 a.a.
• Molecular weight: 14930.64 Da
• Isoelectric Point: 10.4540

>T140988 WP_005180237.1 NZ_CP044445:c2758459-2758067 [Acinetobacter indicus]
MSTAKRDFQLKPSRLALLFQLSLLILFSVLSFQLLHPLLWLLGLLLAAVSYYGFQRRSQLTALAHLDGAEWSLQFNSGSK
IQRGLLEHILDHQLYLVLYFHHAPVKSAVIWRDQVSFAEWKALKTLAKTI

Nucleotide

• Length: 393 bp

>T140988 NZ_CP059588:c4784068-4783916 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9758.15 Da
• Isoelectric Point: 4.9108

>AT140988 WP_171065118.1 NZ_CP044445:c2758691-2758446 [Acinetobacter indicus]
ISLEERKVIYRARRGLKEIDVYFDPYVKNYYLTADPEEKATFAALVEQEDPDLLDWFMEVSEPPRPEMRELIRKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT140988 NZ_CP059588:c4783852-4783718 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Structures

Toxin

• AlphaFold DB: N9KY14