Detailed information of TA system TA140987

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): NpoTA/ParE(toxin)
• Location: 1547196..1548311
• Replicon: chromosome
• Accession: NZ_CP044445
• Organism: Acinetobacter indicus strain CMG3-2

Toxin (Protein)

• Gene name: NpoT
• Uniprot ID: V2U6R6
• Locus tag: FSC02_RS07445
• Protein ID: WP_016658124.1
• Coordinates: 1548147..1548311 (+)
• Length: 55 a.a.

Antitoxin (Protein)

• Gene name: NpoA
• Uniprot ID: -
• Locus tag: FSC02_RS07440
• Protein ID: WP_016658125.1
• Coordinates: 1547196..1548065 (+)
• Length: 290 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FSC02_RS07415	1542485..1543294	-	810	WP_163170107.1	formate/nitrite transporter family protein	-
FSC02_RS07420	1543588..1544037	+	450	WP_127801684.1	cyanase	-
FSC02_RS07425	1544226..1544516	-	291	WP_163170108.1	KGG domain-containing protein	-
FSC02_RS07430	1544954..1546195	-	1242	WP_127799977.1	MFS transporter	-
FSC02_RS07435	1546854..1547093	+	240	WP_163170109.1	DUF2171 domain-containing protein	-
FSC02_RS07440	1547196..1548065	+	870	WP_016658125.1	SDR family oxidoreductase	Antitoxin
FSC02_RS07445	1548147..1548311	+	165	WP_016658124.1	hypothetical protein	Toxin
FSC02_RS07450	1548411..1549829	-	1419	WP_163170110.1	iron-containing redox enzyme family protein	-
FSC02_RS07455	1550131..1551288	-	1158	WP_171065080.1	acyl-CoA desaturase	-
FSC02_RS07460	1551312..1552334	-	1023	WP_160241305.1	ferredoxin reductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 55 a.a.
• Molecular weight: 6182.76 Da
• Isoelectric Point: 10.1466

>T140987 WP_016658124.1 NZ_CP044445:1548147-1548311 [Acinetobacter indicus]
MSRGDKSAYTDKQKRQARHIIESEKERGHSEEEAERIGWSTVNKQDGGGKKKSH

Nucleotide

• Length: 165 bp

>T140987 NZ_CP059588:c4783852-4783718 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin

Protein

• Length: 290 a.a.
• Molecular weight: 31906.00 Da
• Isoelectric Point: 4.8531

>AT140987 WP_016658125.1 NZ_CP044445:1547196-1548065 [Acinetobacter indicus]
MNHYPDSPSPQEKQEHQPGVQYKMTPEPEIIKSNYQGSQKLKDKVALITGGDSGIGRSVAVLFAREGANIIIPYLEEDQD
AQDTKRLVEQEGRQCLLIQCDLRQHAAVQQMVDLALQQFPHINILVNNAAVQYPQKTIEDINPEQLHKTFETNLYPLFYV
TQLLIPQMQPGDSIINTTSITSYQGHNELIDYASTKGAITAFTRSLSTNLLKNKTGIRVNGVAPGPIWTPLIPSSFDEEQ
LKGFGEDTPMGRMGQPSEVAPAYLFLASDEASYISGQVIHVNGGTIVNG

Nucleotide

• Length: 870 bp

>AT140987 NZ_CP059588:c4784068-4783916 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Structures

Toxin

• AlphaFold DB: V2U6R6