Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 708200..708728 Replicon chromosome
Accession NZ_CP044445
Organism Acinetobacter indicus strain CMG3-2

Toxin (Protein)


Gene name relE Uniprot ID N9N871
Locus tag FSC02_RS03360 Protein ID WP_000221358.1
Coordinates 708200..708493 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID N9B5Q7
Locus tag FSC02_RS03365 Protein ID WP_000246756.1
Coordinates 708483..708728 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FSC02_RS03340 704246..704650 + 405 WP_127800837.1 NUDIX domain-containing protein -
FSC02_RS03345 704733..705656 - 924 WP_127800843.1 tRNA-dihydrouridine synthase -
FSC02_RS03350 705922..706695 - 774 WP_127800940.1 glucose 1-dehydrogenase -
FSC02_RS03355 706793..707998 - 1206 WP_171457096.1 alpha/beta fold hydrolase -
FSC02_RS03360 708200..708493 - 294 WP_000221358.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FSC02_RS03365 708483..708728 - 246 WP_000246756.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FSC02_RS03370 708887..709117 + 231 WP_127800942.1 hypothetical protein -
FSC02_RS03375 709129..710069 - 941 Protein_641 IS5 family transposase -
FSC02_RS03380 710419..710838 + 420 WP_039255596.1 PPC domain-containing protein -
FSC02_RS03385 711194..711547 + 354 Protein_643 transposase family protein -
FSC02_RS03390 711587..712141 + 555 WP_127798694.1 hypothetical protein -
FSC02_RS03395 712337..713146 - 810 WP_016659852.1 cytochrome c biogenesis protein CcsA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-71)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11292.52 Da        Isoelectric Point: 10.4753

>T140986 WP_000221358.1 NZ_CP044445:c708493-708200 [Acinetobacter indicus]
MTYKLLRHKDFTAEWEKLPVAIRDQFKKKLAKVIEQPHIPKNMLRGDLAGCYKIKLLKAGVRLVYQVKDDQVVILLITVG
KRADSIVYDEAKKRIKD

Download         Length: 294 bp

>T140986 NZ_CP059588:c2838136-2837885 [Xanthomonas oryzae pv. oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCCTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9235.61 Da        Isoelectric Point: 4.3142

>AT140986 WP_000246756.1 NZ_CP044445:c708728-708483 [Acinetobacter indicus]
MATVNFRVDEALKEKSYSILKEQGIAPTDFFTSILEYVATTGKLPVKKALLSEEDEELLALVRKRINDPKEMFEEVTLDD
L

Download         Length: 246 bp

>AT140986 NZ_CP059588:c2838441-2838163 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6A1RKP4

Antitoxin

Source ID Structure
AlphaFold DB N9B5Q7

References