Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2727795..2728284 Replicon chromosome
Accession NZ_CP044399
Organism Moritella marina ATCC 15381 strain MP-1

Toxin (Protein)


Gene name - Uniprot ID A0A5J6WKN7
Locus tag FR932_RS12200 Protein ID WP_019443015.1
Coordinates 2728018..2728284 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A5J6WK80
Locus tag FR932_RS12195 Protein ID WP_019443014.1
Coordinates 2727795..2728031 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FR932_RS12180 2722996..2725389 + 2394 WP_019443010.1 alpha-glucosidase -
FR932_RS12185 2725595..2725849 + 255 WP_151676834.1 hypothetical protein -
FR932_RS12190 2726030..2727317 - 1288 Protein_2349 helix-turn-helix domain-containing protein -
FR932_RS12195 2727795..2728031 - 237 WP_019443014.1 hypothetical protein Antitoxin
FR932_RS12200 2728018..2728284 - 267 WP_019443015.1 BrnT family toxin Toxin
FR932_RS12205 2728400..2729644 - 1245 WP_019443016.1 RHS repeat-associated core domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10365.46 Da        Isoelectric Point: 6.7237

>T140817 WP_019443015.1 NZ_CP044399:c2728284-2728018 [Moritella marina ATCC 15381]
MNNFEYDPNKSQANFDKHGIDFDDAKSLWNDPNLIEIPANTSDEARFVIIAFHNGKHWSAVITYRNNNIRIISVRRSRKN
EVTFYESF

Download         Length: 267 bp

>T140817 NZ_CP059467:3725902-3726090 [Aromatoleum bremense]
ATGAAAAGCACCGACATCATCAAGCGACTGGAGTCAGAAGGCTGGCAGCGCGTCGGTGGCAAGGGCGACCACATAAAGTT
CAAGCATCCCGGCAAGCCCGGCCACGTAGTGGTGCCACACCCGCGCAAGGACGTGGCGATCGGCACGCTGCGCAACATCT
ACCGGCAGGCCGGATGGGATTGGAGGTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9103.26 Da        Isoelectric Point: 6.4650

>AT140817 WP_019443014.1 NZ_CP044399:c2728031-2727795 [Moritella marina ATCC 15381]
MKASNFDKKFDEGNDVLADLDLSQAKRTTQITKRVNVDFPEWMIDSLDREASRVGVTRQSIIKVWLAERIENLNHHNF

Download         Length: 237 bp

>AT140817 NZ_CP059467:3726096-3726485 [Aromatoleum bremense]
ATGTTGTATCCCGTGTACGTGCATAAGGACGAAGGCAGCGCCTACGGGCTGACCTTCCCGGATTTTCCGGGCTGCTTTTC
CGCTGCGGACGAATTGGCTGACCTGCCGCGCATGGCGCAGGAGGCCGTGGAGGTGCATTTCGAGGGGGAGAACATGGCGA
TCCCGAAGCCGTCCGCCCCCGAGCAATGGGGCGATGATGAGCGCTTCCACGGTGGGTACTGGATGCTGGTGGAAATCGAC
CTGGCGCGGGTGAGCGCAAGGCCCGTGCGGCTGAATATCTCGCTTCCGGAATACCTGGTGCGGCAGATCGACGCCTATGC
CGCGTCCCATCATCAAAGCCGGTCGGGCTTTCTTGCCCGGGCGGCAGAAGAGGCGATGCGAGCGCGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5J6WKN7

Antitoxin

Source ID Structure
AlphaFold DB A0A5J6WK80

References