Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3357903..3358544 Replicon chromosome
Accession NZ_CP044356
Organism Acinetobacter baumannii strain CAM180-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag ABCAM1_RS16475 Protein ID WP_032036174.1
Coordinates 3357903..3358292 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ABCAM1_RS16480 Protein ID WP_011860336.1
Coordinates 3358299..3358544 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABCAM1_RS16455 3353245..3355299 + 2055 WP_004839673.1 M3 family metallopeptidase -
ABCAM1_RS16460 3355340..3355549 + 210 WP_000745518.1 YheV family putative metal-binding protein -
ABCAM1_RS16465 3355561..3355992 + 432 Protein_3162 hypothetical protein -
ABCAM1_RS16470 3356184..3357116 - 933 WP_001040037.1 IS5-like element ISAha2 family transposase -
ABCAM1_RS16475 3357903..3358292 - 390 WP_032036174.1 membrane protein Toxin
ABCAM1_RS16480 3358299..3358544 - 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
ABCAM1_RS16485 3358744..3359916 + 1173 WP_031961342.1 acyl-CoA dehydrogenase family protein -
ABCAM1_RS16490 3359965..3361455 - 1491 WP_032036176.1 NAD(P)/FAD-dependent oxidoreductase -
ABCAM1_RS16495 3361637..3362014 - 378 WP_001216380.1 50S ribosomal protein L17 -
ABCAM1_RS16500 3362033..3363040 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3356184..3357116 932


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15641.96 Da        Isoelectric Point: 10.5620

>T140805 WP_032036174.1 NZ_CP044356:c3358292-3357903 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLTQIAYLDKKLWSLAYQSQNTV
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAKWKKLKTLEKLY

Download         Length: 390 bp

>T140805 NZ_CP059447:c3210957-3210532 [Cellulosimicrobium cellulans]
GTGATCGTCCTCGACACGAACGTCGTCTCGGAGCTCACGAGGACGACGCCGGAGCGCTCCGTGGTGCGATGGCTCGACGG
CGTGCCGCCGCTGGACGTCTGGCTCACGTCGATCACGATCGCGGAGATGTCGTACGGTATCGCCCGGTTGGTGGCCGGTC
GGCGCCGGGACGAGCTCGTCGTACGCGTCGAGACGGTTATCGACGGCCTCGGCGGTCAGGTGCTGTCGTTCGACCAGGAG
GCCGCCCACGCGTTCGGCGCCGTCATGGCCGGACGAGACCGCGCTGGGCAACCCATCGGTACCGCGGACGCGCAGATCGC
CGCGATCTGTCGCGTGCACGACGCGACGCTCGCGACGCGCAACGTCCGCGACTTCGTCGGCACCGGCGTCGCCGTCGTCG
ACCCGTGGAGAACCGCGCCTTCCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT140805 WP_011860336.1 NZ_CP044356:c3358544-3358299 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT140805 NZ_CP059447:c3211214-3210954 [Cellulosimicrobium cellulans]
ATGGCGACGCTGACGATCCGAGGGCTCGACGACGACGTGCGCGAACGGCTGCGTGCGCGCGCCGTCGAGCACGGGCGGTC
CATGGAGGCGGAGGTGCGCGAGATCCTTGCCGCTGCCGTTCGCTCTCCGAGCGGGGTCGAGCGCGGTCTCGGGACCTGGA
TCGCCGAGACCTTCGCCGGGATCGGCGGGACCGAGGCGGACGTGTTCGACGTGCGCCGCGATGATCGCCCTCGCGTGGTC
GACTTCAGCGACCCGACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References