Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 114123..114636 Replicon chromosome
Accession NZ_CP044356
Organism Acinetobacter baumannii strain CAM180-1

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2L2M0A2
Locus tag ABCAM1_RS00560 Protein ID WP_000203952.1
Coordinates 114123..114386 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S7WSW9
Locus tag ABCAM1_RS00565 Protein ID WP_000557943.1
Coordinates 114373..114636 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABCAM1_RS00525 110213..111643 + 1431 WP_000178999.1 amino acid permease -
ABCAM1_RS00530 111701..112045 - 345 Protein_100 LysR family transcriptional regulator -
ABCAM1_RS00535 112084..113317 - 1234 Protein_101 IS3 family transposase -
ABCAM1_RS00540 113376..113693 - 318 Protein_102 LysR family transcriptional regulator -
ABCAM1_RS00550 113827..113925 + 99 Protein_103 IS5/IS1182 family transposase -
ABCAM1_RS00555 113957..114064 - 108 Protein_104 transposase domain-containing protein -
ABCAM1_RS00560 114123..114386 - 264 WP_000203952.1 Txe/YoeB family addiction module toxin Toxin
ABCAM1_RS00565 114373..114636 - 264 WP_000557943.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ABCAM1_RS00570 115052..118399 + 3348 WP_103270920.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10664.10 Da        Isoelectric Point: 8.4894

>T140802 WP_000203952.1 NZ_CP044356:c114386-114123 [Acinetobacter baumannii]
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

>T140802 NZ_CP059446:29638-30279 [Campylobacter fetus]
GTGAATGATATCTTTGAAGAGCTAATTACAAACAATAAATTAGGAATTAAAAACTATGACGAATTTGAAAAAATAAGCAG
AAAATATACTGCTAATAGAATATTTGAAATTCAAAAAAATCCCATAAAAGGAAATTTTGATTATCAGCACTTAAAAGATA
CTCATAAATTTGTTTTCCAAGATGTTTTTGAATGGGCTGGAAAAGATAGGGCTGAGCTTGGGTTACTTGATACTTTTGCT
AAACGATCACCATTTAATCCAAATCACATACAAAATTTCGTTCCAGGTAAAGAGCTTGAAAAATACTCAAAAATAATCTT
TGATGAGCTAAAAGAACAAAACTATCTAAAAAATAGTAAAGATTTAAATACATTTACAAAAGGCATGGCAAATTTTTTAA
TGGAGTTAAACGCACTTCATCCATTTCGTGAAGGAAATGGTAGAACGGGGAGAATATTTTGCAATGAGTTAGCCAAAAAT
GCAGGATATAAAATGGATCTAAATTTAATTCCAAAAGAAAAATTAATAACAGCTTCCATAGAAGCTATGGAGTGTAAAAA
TGCAAAACTTGAAGCATTAATAAAAGCAAATTTAAAGATTTTTAAACAAAATTTAACCAAAGAACAAGGGATATCTTTTT
AA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9841.04 Da        Isoelectric Point: 5.5940

>AT140802 WP_000557943.1 NZ_CP044356:c114636-114373 [Acinetobacter baumannii]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES

Download         Length: 264 bp

>AT140802 NZ_CP059446:29408-29641 [Campylobacter fetus]
ATGAAAAATTATCCAGAAGTTTATAGCTTAGAAGAGAGTTTGGAAATACTAAAAAAGTATAGAAATGAAATTAGCAAAGA
TGATTATGACAATATAAAATCAGTCATAGGCTCTCACGCAATAGAAAGTCAATATTTAAATGAAATAGATATAGAAATGC
TTGTAGATAAGGCAATAAATAATAGAACAACAGAAGAATCAATAAATAGACTAAAAAATAAAGGCTTATTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L2M0A2

Antitoxin

Source ID Structure
AlphaFold DB S7WSW9

References