140704

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3183499..3183868 Replicon chromosome
Accession NZ_CP044334
Organism Xanthomonas arboricola pv. pruni strain 15-088

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag F6Y24_RS14030 Protein ID WP_016904515.1
Coordinates 3183734..3183868 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag F6Y24_RS14025 Protein ID WP_006451340.1
Coordinates 3183499..3183651 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F6Y24_RS14000 3179565..3180107 - 543 WP_016904520.1 GTPase -
F6Y24_RS14005 3180104..3181021 - 918 WP_039512632.1 hypothetical protein -
F6Y24_RS14010 3181115..3181474 - 360 WP_039512630.1 hypothetical protein -
F6Y24_RS14015 3181538..3181990 - 453 WP_039512628.1 roadblock/LC7 domain-containing protein -
F6Y24_RS14020 3182466..3183389 + 924 WP_039512664.1 arginase -
F6Y24_RS14025 3183499..3183651 + 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
F6Y24_RS14030 3183734..3183868 + 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
F6Y24_RS14035 3184119..3184328 + 210 WP_039512625.1 CsbD family protein -
F6Y24_RS14040 3184510..3185799 + 1290 WP_039814994.1 tryptophan--tRNA ligase -
F6Y24_RS14045 3185857..3186801 + 945 WP_039512622.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T140704 WP_016904515.1 NZ_CP044334:3183734-3183868 [Xanthomonas arboricola pv. pruni]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T140704 NZ_CP059349:448642-449031 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT140704 WP_006451340.1 NZ_CP044334:3183499-3183651 [Xanthomonas arboricola pv. pruni]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT140704 NZ_CP059349:448378-448635 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References