Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2716405..2716949 Replicon chromosome
Accession NZ_CP044334
Organism Xanthomonas arboricola pv. pruni strain 15-088

Toxin (Protein)


Gene name relE Uniprot ID A0A2N7V9Q0
Locus tag F6Y24_RS12135 Protein ID WP_016902923.1
Coordinates 2716405..2716704 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2N7V9L6
Locus tag F6Y24_RS12140 Protein ID WP_016902922.1
Coordinates 2716692..2716949 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F6Y24_RS12105 2711676..2712569 + 894 WP_043087408.1 LysR family transcriptional regulator -
F6Y24_RS12110 2712580..2713293 - 714 WP_039511101.1 hypothetical protein -
F6Y24_RS12115 2713751..2714842 + 1092 WP_039511112.1 hypothetical protein -
F6Y24_RS12120 2715002..2715242 - 241 Protein_2294 hypothetical protein -
F6Y24_RS12125 2715256..2715594 + 339 Protein_2295 helix-turn-helix transcriptional regulator -
F6Y24_RS12130 2715765..2716286 + 522 WP_051633992.1 hypothetical protein -
F6Y24_RS12135 2716405..2716704 - 300 WP_016902923.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F6Y24_RS12140 2716692..2716949 - 258 WP_016902922.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
F6Y24_RS12145 2717005..2717667 - 663 WP_039511099.1 hemolysin III family protein -
F6Y24_RS12150 2717841..2720336 + 2496 WP_043087409.1 DEAD/DEAH box helicase -
F6Y24_RS12155 2720333..2721841 + 1509 WP_043087410.1 ribonuclease H-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2706657..2716949 10292


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11336.04 Da        Isoelectric Point: 9.0225

>T140702 WP_016902923.1 NZ_CP044334:c2716704-2716405 [Xanthomonas arboricola pv. pruni]
MAEIVWSEPAVADLDAIADYIALEDAAAAAALVRRVFAHVEQLAEHPESGSRPQELKRSRYRQIVEPPCRVFYRVDGQRV
VVVHVMRSERLLRKNRLSR

Download         Length: 300 bp

>T140702 NZ_CP059348:3971759-3972013 [Providencia rettgeri]
ATGAAAACCATTTCCTTTAGTGATGCGAGAAGCAATTTGAAAGCCGTGCTTGATAGAGTTGTTGATGATATGGATACGAC
GATTATAACCCGCCGTGATTCTGAAGCGGCTGTAGTTATGTCCTTGGAATACTACAATAGTTTAATGGAAACCATCTATC
TATTGCGCTCTCCTGCAAATGCAGAGCATCTCAACAAGTCCATCGAGCAATTTAAAGCGGGTAAGATTTCAGAGAGAAAG
CTAATCAATGAGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9704.23 Da        Isoelectric Point: 8.6056

>AT140702 WP_016902922.1 NZ_CP044334:c2716949-2716692 [Xanthomonas arboricola pv. pruni]
MRTELVTTLKRQATELLADVERDKEPILITQHGLPSAYLVDVASYERMQQRMAILEGIARGEMAVAEGRSLSHEQAKQRL
ARWLK

Download         Length: 258 bp

>AT140702 NZ_CP059348:3972006-3972266 [Providencia rettgeri]
ATGAGTAGACTTCTAACATGGACGGATCAAGCTTGGGATGATTATCTATACTGGCAAAGCCAAGATAAAAAGACATTAAA
GCGGATCAATAAACTCATTGAAGACACAAAAAGAACGCCATTCAGCGGTATAGGTAAACCAGAGCCACTAAAAGAAAACT
TAGCTGGCTTCTGGTCTCGTAGAATAGATGAAACGAATAGGCTAGTTTATGCAATCGAAAATACCGCACTAGTCATCATT
GCCTGTCGCTATCATTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N7V9Q0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V9L6

References