Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 254659..255380 Replicon chromosome
Accession NZ_CP044331
Organism Methylocystis parvus strain BRCS2

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag F7D14_RS01190 Protein ID WP_202948247.1
Coordinates 254659..255045 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag F7D14_RS01195 Protein ID WP_016918880.1
Coordinates 255144..255380 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F7D14_RS01175 249798..252425 - 2628 WP_016918884.1 ATP-dependent chaperone ClpB -
F7D14_RS01180 252804..253367 + 564 WP_016918883.1 ATP-dependent protease subunit HslV -
F7D14_RS01185 253368..254669 + 1302 WP_016918882.1 ATP-dependent protease ATPase subunit HslU -
F7D14_RS01190 254659..255045 - 387 WP_202948247.1 GNAT family N-acetyltransferase Toxin
F7D14_RS01195 255144..255380 - 237 WP_016918880.1 DUF1778 domain-containing protein Antitoxin
F7D14_RS01200 255560..256594 + 1035 WP_016918879.1 tryptophan--tRNA ligase -
F7D14_RS01205 256646..257950 - 1305 WP_016918878.1 glycolate oxidase subunit GlcF -
F7D14_RS01210 257950..259167 - 1218 WP_016918877.1 glycolate oxidase subunit GlcE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(9-111)

Antitoxin

Vibrio phage ICP1, Orf50

(3-77)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14060.39 Da        Isoelectric Point: 11.0108

>T140697 WP_202948247.1 NZ_CP044331:c255045-254659 [Methylocystis parvus]
MPNQLTGASRTFVISRDERVVGYYALAAGAIASHEAPSRLSRNMPDPIPVFILGRLAVDRSEQGRMLGSLLLRDAIIRTR
AAAEFGGIAGLLVHALSVEAKRFYMHRGFVESPSRPMTLLARLKDIKE

Download         Length: 387 bp

>T140697 NZ_CP059348:c967045-966842 [Providencia rettgeri]
ATGACCAAATCCGATTATCTGATGCGTTTAAGAAAATGCACCACTATTGAAACACTTGAGCGCGTCATTGAGAAAAATAA
GTATGAGTTATCTGATGATGAATTAGAGTTATTTTACTCTGCAGCAGATCATCGTCTTGCCGAACTCACCATGAATAAAC
TTTACGATAAAATCCCAGCATCTGTTTGGAAGTTTGTTAGATAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8683.93 Da        Isoelectric Point: 7.0122

>AT140697 WP_016918880.1 NZ_CP044331:c255380-255144 [Methylocystis parvus]
MAAEDRNIIDQAARIAGKSRTEFMVEAARRAAQDTVLDANLIVVDGKTFEQFRAIFDAPAKPNAHIQKLMNLKAPWES

Download         Length: 237 bp

>AT140697 NZ_CP059348:c967486-967118 [Providencia rettgeri]
ATGGATGAATACTCACCCAAGAAACATGATATAGCCGAATTAAAATATCTGTGTAACAGTTTGAATAGAGACGCAATATC
AAGTTTACAAAAAACAAACACCCATTGGGTAAATGATCTTAGTTCGCCACAAAGCATCAGTCTCAATGAGCTCGTTGAGC
ATATTGCAGCTTTTGTCTGGCGATTCAAAATCAAGTATCCAAAAGAAAATCTCGTTATTTCTCTTGTTGAAGAGTATCTT
GACGAGACATATAATTTATTTGGCAGCCCAGTAATTACTTTCAGCGAAATCATTGACTGGGAAAGTATGAATCAAAATCT
TGTCGCCGTGCTCGATGATGATCTAAAATGCCTGACAAGTAAGACATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References