Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1854788..1855059 Replicon chromosome
Accession NZ_CP044311
Organism Escherichia coli strain RM13752

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1854826..1854929 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1854788..1855059 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F7D06_RS09210 1851945..1853384 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
F7D06_RS09215 1853502..1853738 + 237 WP_001295499.1 DUF1480 family protein -
F7D06_RS09220 1853843..1854034 + 192 WP_001296140.1 YebW family protein -
F7D06_RS09225 1854035..1854691 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1854788..1855059 + 272 - - Antitoxin
- 1854826..1854929 - 104 - - Toxin
F7D06_RS09230 1855087..1855428 - 342 WP_000976492.1 YebY family protein -
F7D06_RS09235 1855441..1856313 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
F7D06_RS09240 1856317..1856691 - 375 WP_000204699.1 CopC domain-containing protein YobA -
F7D06_RS09245 1856830..1857060 + 231 WP_000916763.1 DNA polymerase III subunit theta -
F7D06_RS09250 1857162..1857818 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
F7D06_RS09255 1857842..1858504 + 663 WP_050939619.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T140556 NZ_CP044311:c1854929-1854826 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT140556 NZ_CP044311:1854788-1855059 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References