Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FicTA/Fic(toxin)
Location 20203..21079 Replicon plasmid pCA639-2
Accession NZ_CP044263
Organism Campylobacter armoricus strain CA639

Toxin (Protein)


Gene name Fic Uniprot ID -
Locus tag F6X58_RS08775 Protein ID WP_139454154.1
Coordinates 20203..20841 (-) Length 213 a.a.

Antitoxin (Protein)


Gene name Fti Uniprot ID -
Locus tag F6X58_RS08780 Protein ID WP_057039917.1
Coordinates 20825..21079 (-) Length 85 a.a.

Genomic Context

F6X58_RS08740F6X58_RS08745F6X58_RS08750F6X58_RS08755F6X58_RS08760F6X58_RS08765F6X58_RS08770F6X58_RS08775F6X58_RS08780F6X58_RS08785F6X58_RS08790F6X58_RS08795F6X58_RS08995
Location: 15976..16182 (207 bp)
Type: Others
Protein ID: WP_139454149.1
Location: 16273..17358 (1086 bp)
Type: Others
Protein ID: WP_126267761.1
Location: 17358..18185 (828 bp)
Type: Others
Protein ID: WP_126267760.1
Location: 18277..18501 (225 bp)
Type: Others
Protein ID: WP_139454150.1
Location: 18504..19190 (687 bp)
Type: Others
Protein ID: WP_139454151.1
Location: 19271..19666 (396 bp)
Type: Others
Protein ID: WP_139454152.1
Location: 19731..20198 (468 bp)
Type: Others
Protein ID: WP_139454153.1
Location: 20203..20841 (639 bp)
Type: Toxin
Protein ID: WP_139454154.1
Location: 20825..21079 (255 bp)
Type: Antitoxin
Protein ID: WP_057039917.1
Location: 21171..21890 (720 bp)
Type: Others
Protein ID: WP_139454155.1
Location: 21901..23724 (1824 bp)
Type: Others
Protein ID: WP_139454156.1
Location: 23721..25931 (2211 bp)
Type: Others
Protein ID: WP_139454157.1
Location: 25936..26076 (141 bp)
Type: Others
Protein ID: WP_167507515.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
F6X58_RS0874015976..16182-207WP_139454149.1hypothetical protein-
F6X58_RS0874516273..17358-1086WP_126267761.1site-specific DNA-methyltransferase-
F6X58_RS0875017358..18185-828WP_126267760.1type II restriction endonuclease-
F6X58_RS0875518277..18501-225WP_139454150.1hypothetical protein-
F6X58_RS0876018504..19190-687WP_139454151.1AAA family ATPase-
F6X58_RS0876519271..19666-396WP_139454152.1conjugal transfer protein TraM-
F6X58_RS0877019731..20198-468WP_139454153.1signal peptidase I-
F6X58_RS0877520203..20841-639WP_139454154.1Fic family proteinToxin
F6X58_RS0878020825..21079-255WP_057039917.1hypothetical proteinAntitoxin
F6X58_RS0878521171..21890-720WP_139454155.1conjugal transfer protein TraL-
F6X58_RS0879021901..23724-1824WP_139454156.1type IV secretory system conjugative DNA transfer family protein-
F6X58_RS0879523721..25931-2211WP_139454157.1DUF1738 domain-containing protein-
F6X58_RS0899525936..26076-141WP_167507515.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..2814028140


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(50-154)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 213 a.a.        Molecular weight: 24456.98 Da        Isoelectric Point: 9.6243

>T140508 WP_139454154.1 NZ_CP044263:c20841-20203 [Campylobacter armoricus]
MKESNEELFKRLITDNKLGIKDEKLFDKASRFYTGLRERELTLNPIKGNFDYQHLKNIHKHIFQDVFYWAGKDRMEVGLS
SFMSKGDSLFCSAEYIPGEAKKIFDELAKNNYLKNSKDLNHFAKDLANFISDLNALHPFREGNGRTQRIFLNELAKNAGY
KLDLNLISKEKMIEASIEAMGGRNGKLEAVIKTNLKNFRQNLDLEQNKGISL

Download         Length: 639 bp

>T140508 NZ_CP059288:c583368-582922 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9812.20 Da        Isoelectric Point: 4.7225

>AT140508 WP_057039917.1 NZ_CP044263:c21079-20825 [Campylobacter armoricus]
MQKQYPEVHSLEESLAILKKYKDDVNKEDYEGIKSVISNHAIESIYMNELDIIAMIKQSALKLSADEIIAEYKEKGFVEY
ERKQ

Download         Length: 255 bp

>AT140508 NZ_CP059288:c583703-583368 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References