Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2009987..2010132 Replicon chromosome
Accession NZ_CP044258
Organism Klebsiella pneumoniae strain KP65

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2010023..2010125 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2009987..2010132 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F6W81_RS10005 2005117..2007177 + 2061 WP_004151449.1 oligopeptidase B -
F6W81_RS10010 2007181..2007840 - 660 WP_002911407.1 exodeoxyribonuclease X -
F6W81_RS10015 2007919..2008149 - 231 WP_002911406.1 DNA polymerase III subunit theta -
F6W81_RS10020 2008262..2008636 + 375 WP_004151448.1 CopC domain-containing protein YobA -
F6W81_RS10025 2008640..2009509 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
F6W81_RS10030 2009526..2009864 + 339 WP_002911404.1 YebY family protein -
- 2009987..2010132 - 146 - - Antitoxin
- 2010023..2010125 + 103 - - Toxin
F6W81_RS10040 2010500..2010643 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
F6W81_RS10045 2010748..2011716 - 969 WP_004151446.1 VirK/YbjX family protein -
F6W81_RS10050 2011873..2012526 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
F6W81_RS10055 2012523..2012714 - 192 WP_002911395.1 YebW family protein -
F6W81_RS10060 2012812..2013051 - 240 WP_002911393.1 YebV family protein -
F6W81_RS10065 2013167..2014600 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T140486 NZ_CP044258:2010023-2010125 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT140486 NZ_CP044258:c2010132-2009987 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References