Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 1602939..1603732 Replicon chromosome
Accession NZ_CP044222
Organism Nitrincola sp. KXZD1103

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag F5I99_RS07275 Protein ID WP_151054543.1
Coordinates 1602939..1603475 (-) Length 179 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag F5I99_RS07280 Protein ID WP_151054545.1
Coordinates 1603466..1603732 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F5I99_RS07250 1598848..1599171 - 324 WP_151054534.1 helix-turn-helix domain-containing protein -
F5I99_RS07255 1599378..1600178 - 801 WP_151054536.1 transglutaminase family protein -
F5I99_RS07260 1600413..1600940 - 528 WP_151054537.1 GNAT family N-acetyltransferase -
F5I99_RS07265 1600937..1601215 - 279 WP_151054539.1 DUF1778 domain-containing protein -
F5I99_RS07270 1601356..1602903 - 1548 WP_151054541.1 plasmid pRiA4b ORF-3 family protein -
F5I99_RS07275 1602939..1603475 - 537 WP_151054543.1 GNAT family N-acetyltransferase Toxin
F5I99_RS07280 1603466..1603732 - 267 WP_151054545.1 DUF1778 domain-containing protein Antitoxin
F5I99_RS07285 1603855..1604406 - 552 WP_151054547.1 pyridoxamine 5'-phosphate oxidase family protein -
F5I99_RS07290 1604792..1605889 - 1098 WP_151054549.1 tyrosine-type recombinase/integrase -
F5I99_RS07295 1605867..1606088 - 222 WP_151054551.1 helix-turn-helix domain-containing protein -
F5I99_RS07300 1606078..1606344 - 267 WP_151054553.1 hypothetical protein -
F5I99_RS07305 1606347..1606691 - 345 WP_151054555.1 hypothetical protein -
F5I99_RS07310 1606688..1607059 - 372 WP_151054557.1 hypothetical protein -
F5I99_RS07315 1607052..1607309 - 258 WP_151054559.1 hypothetical protein -
F5I99_RS07320 1607309..1607689 - 381 WP_151054561.1 hypothetical protein -
F5I99_RS07325 1607682..1608008 - 327 WP_151054563.1 hypothetical protein -
F5I99_RS07330 1608001..1608621 - 621 WP_151054565.1 HNH endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-146)

Antitoxin

Vibrio phage ICP1, Orf50

(8-83)


Sequences

Toxin        


Download         Length: 179 a.a.        Molecular weight: 19486.70 Da        Isoelectric Point: 9.7197

>T140466 WP_151054543.1 NZ_CP044222:c1603475-1602939 [Nitrincola sp. KXZD1103]
MGISAPTLLTDQHQLNPFQCGIEELDIWLSKQALKSQKRGTARVYVVNDTKTRQVVGYYAIAMGSVSREHAFSSLRRNSP
EPIPMVILARLGVDSAYQGRGIAAGLLKDCILRSIQAMNAVGGAGILVHAIDPSAQSFYKKFGFKESALDPLVLMARICD
IEKTLTHHSLFLRFGLIG

Download         Length: 537 bp

>T140466 NZ_CP059281:c478737-478630 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9954.46 Da        Isoelectric Point: 5.1299

>AT140466 WP_151054545.1 NZ_CP044222:c1603732-1603466 [Nitrincola sp. KXZD1103]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAAINEAHNVLAEQRDFVLEAKAFEAFDLELRAEPQTLEGMKDL
FNRKAPWE

Download         Length: 267 bp

>AT140466 NZ_CP059281:478786-478851 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References