Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1600413..1601215 Replicon chromosome
Accession NZ_CP044222
Organism Nitrincola sp. KXZD1103

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag F5I99_RS07260 Protein ID WP_151054537.1
Coordinates 1600413..1600940 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag F5I99_RS07265 Protein ID WP_151054539.1
Coordinates 1600937..1601215 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F5I99_RS07235 1595497..1595667 + 171 WP_151054528.1 RES family NAD+ phosphorylase -
F5I99_RS07240 1595863..1597458 + 1596 WP_151054530.1 diguanylate cyclase -
F5I99_RS07245 1597538..1598854 - 1317 WP_151054532.1 type II toxin-antitoxin system HipA family toxin -
F5I99_RS07250 1598848..1599171 - 324 WP_151054534.1 helix-turn-helix domain-containing protein -
F5I99_RS07255 1599378..1600178 - 801 WP_151054536.1 transglutaminase family protein -
F5I99_RS07260 1600413..1600940 - 528 WP_151054537.1 GNAT family N-acetyltransferase Toxin
F5I99_RS07265 1600937..1601215 - 279 WP_151054539.1 DUF1778 domain-containing protein Antitoxin
F5I99_RS07270 1601356..1602903 - 1548 WP_151054541.1 plasmid pRiA4b ORF-3 family protein -
F5I99_RS07275 1602939..1603475 - 537 WP_151054543.1 GNAT family N-acetyltransferase -
F5I99_RS07280 1603466..1603732 - 267 WP_151054545.1 DUF1778 domain-containing protein -
F5I99_RS07285 1603855..1604406 - 552 WP_151054547.1 pyridoxamine 5'-phosphate oxidase family protein -
F5I99_RS07290 1604792..1605889 - 1098 WP_151054549.1 tyrosine-type recombinase/integrase -
F5I99_RS07295 1605867..1606088 - 222 WP_151054551.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19094.14 Da        Isoelectric Point: 9.3381

>T140465 WP_151054537.1 NZ_CP044222:c1600940-1600413 [Nitrincola sp. KXZD1103]
MMLPAWYEEPIGKSHDRSMFDCGDAALNQFLRLHARQSHEKGAAKTYLAIADEVGKTVMGYYTLSPASIAYERTPEVIKR
GLARHEVPVFRLGRLAVDVSRQGQGLGGQLLLSAGRRCLLVAMQAGGVALLIDAKNERVANWYESYGAIPLLDAPLSLIL
SFRTIHTALTAAGKL

Download         Length: 528 bp

>T140465 NZ_CP059281:c478254-478147 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGTTCCGGTCATTACTGGCATTCTTGCCAGTATGAT
CGTGAGCTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10182.90 Da        Isoelectric Point: 7.2047

>AT140465 WP_151054539.1 NZ_CP044222:c1601215-1600937 [Nitrincola sp. KXZD1103]
MPQIPVGTNERVSLRIASEEKLLLMRAAALQHTNLTEFVISNVVSVAQKIIDEHERLSLTERDSLRMLALLDNPPAPNDK
LMAAALSLPKRA

Download         Length: 279 bp

>AT140465 NZ_CP059281:478311-478368 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References