Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2190558..2190792 | Replicon | chromosome |
| Accession | NZ_CP044158 | ||
| Organism | Shigella flexneri strain AR-0423 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2190559..2190662 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2190558..2190792 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F4V35_RS11325 | 2186004..2186471 | - | 468 | Protein_2197 | DNA-binding transcriptional regulator PgrR | - |
| F4V35_RS11330 | 2186535..2186845 | + | 311 | Protein_2198 | transposase | - |
| F4V35_RS11335 | 2186888..2188083 | - | 1196 | Protein_2199 | IS3 family transposase | - |
| F4V35_RS11340 | 2188138..2188986 | + | 849 | Protein_2200 | IS3-like element IS600 family transposase | - |
| F4V35_RS11345 | 2189103..2189384 | + | 282 | WP_005127484.1 | excisionase | - |
| F4V35_RS25760 | 2189350..2190427 | + | 1078 | Protein_2202 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2190558..2190792 | + | 235 | - | - | Antitoxin |
| - | 2190559..2190662 | - | 104 | - | - | Toxin |
| F4V35_RS11360 | 2190820..2191161 | - | 342 | WP_000976476.1 | YebY family protein | - |
| F4V35_RS11365 | 2191174..2192046 | - | 873 | Protein_2204 | copper homeostasis membrane protein CopD | - |
| F4V35_RS11370 | 2192050..2192424 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| F4V35_RS11375 | 2192563..2192793 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| F4V35_RS11380 | 2192895..2193551 | + | 657 | Protein_2207 | carbon-nitrogen hydrolase family protein | - |
| F4V35_RS11385 | 2193575..2194237 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T140406 NZ_CP044158:c2190662-2190559 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT140406 NZ_CP044158:2190558-2190792 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
