Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 146330..146564 | Replicon | chromosome |
| Accession | NZ_CP044155 | ||
| Organism | Shigella flexneri strain AR-0424 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 146331..146434 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 146330..146564 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F4V36_RS00675 | 141776..142243 | - | 468 | Protein_135 | DNA-binding transcriptional regulator PgrR | - |
| F4V36_RS00680 | 142307..142617 | + | 311 | Protein_136 | transposase | - |
| F4V36_RS00685 | 142660..143855 | - | 1196 | Protein_137 | IS3 family transposase | - |
| F4V36_RS00690 | 143910..144758 | + | 849 | Protein_138 | IS3-like element IS600 family transposase | - |
| F4V36_RS00695 | 144875..145156 | + | 282 | WP_005127484.1 | excisionase | - |
| F4V36_RS25855 | 145122..146199 | + | 1078 | Protein_140 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 146330..146564 | + | 235 | - | - | Antitoxin |
| - | 146331..146434 | - | 104 | - | - | Toxin |
| F4V36_RS00710 | 146592..146933 | - | 342 | WP_000976476.1 | YebY family protein | - |
| F4V36_RS00715 | 146946..147818 | - | 873 | Protein_142 | copper homeostasis membrane protein CopD | - |
| F4V36_RS00720 | 147822..148196 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| F4V36_RS00725 | 148335..148565 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| F4V36_RS00730 | 148667..149323 | + | 657 | Protein_145 | carbon-nitrogen hydrolase family protein | - |
| F4V36_RS00735 | 149347..150009 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T140365 NZ_CP044155:c146434-146331 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT140365 NZ_CP044155:146330-146564 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
