Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 35204..35438 | Replicon | chromosome |
| Accession | NZ_CP044152 | ||
| Organism | Shigella flexneri strain AR-0425 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 35334..35437 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 35204..35438 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F4V37_RS00170 | 31759..32421 | - | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
| F4V37_RS00175 | 32445..33101 | - | 657 | Protein_34 | carbon-nitrogen hydrolase family protein | - |
| F4V37_RS00180 | 33203..33433 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| F4V37_RS00185 | 33572..33946 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| F4V37_RS00190 | 33950..34822 | + | 873 | Protein_37 | copper homeostasis membrane protein CopD | - |
| F4V37_RS00195 | 34835..35176 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 35204..35438 | - | 235 | - | - | Antitoxin |
| - | 35334..35437 | + | 104 | - | - | Toxin |
| F4V37_RS25245 | 35569..36646 | - | 1078 | Protein_39 | phage integrase Arm DNA-binding domain-containing protein | - |
| F4V37_RS00210 | 36612..36893 | - | 282 | WP_005127484.1 | excisionase | - |
| F4V37_RS00215 | 37010..37858 | - | 849 | Protein_41 | IS3-like element IS600 family transposase | - |
| F4V37_RS00220 | 37913..39108 | + | 1196 | Protein_42 | IS3 family transposase | - |
| F4V37_RS00225 | 39151..39461 | - | 311 | Protein_43 | transposase | - |
| F4V37_RS00230 | 39525..39992 | + | 468 | Protein_44 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 9853..39992 | 30139 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T140338 NZ_CP044152:35334-35437 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT140338 NZ_CP044152:c35438-35204 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
