Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 138084..138318 Replicon chromosome
Accession NZ_CP044151
Organism Shigella sonnei strain AR-0426

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 138214..138317 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 138084..138318 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F4V38_RS00790 134639..135301 - 663 WP_000944256.1 exodeoxyribonuclease X -
F4V38_RS00795 135325..135981 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
F4V38_RS00800 136083..136313 - 231 WP_000916763.1 DNA polymerase III subunit theta -
F4V38_RS00805 136452..136826 + 375 WP_000168735.1 CopC domain-containing protein YobA -
F4V38_RS00810 136830..137702 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
F4V38_RS00815 137715..138056 + 342 WP_151089707.1 YebY family protein -
- 138084..138318 - 235 - - Antitoxin
- 138214..138317 + 104 - - Toxin
F4V38_RS00820 138449..139525 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
F4V38_RS00840 141621..141737 - 117 Protein_154 host-nuclease inhibitor Gam family protein -
F4V38_RS00845 141715..142035 - 321 WP_241556168.1 exodeoxyribonuclease VIII -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 130674..166785 36111


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T140319 NZ_CP044151:138214-138317 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT140319 NZ_CP044151:c138318-138084 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGATAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References