Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 629827..630098 Replicon chromosome
Accession NZ_CP044148
Organism Escherichia coli O157 strain AR-0427

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 629865..629968 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 629827..630098 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F4V39_RS03205 626984..628423 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
F4V39_RS03210 628541..628777 + 237 WP_001295499.1 DUF1480 family protein -
F4V39_RS03215 628882..629073 + 192 WP_001296140.1 YebW family protein -
F4V39_RS03220 629074..629730 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 629827..630098 + 272 - - Antitoxin
- 629865..629968 - 104 - - Toxin
F4V39_RS03225 630126..630467 - 342 WP_000976483.1 YebY family protein -
F4V39_RS03230 630480..631352 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
F4V39_RS03235 631356..631730 - 375 WP_000168751.1 CopC domain-containing protein YobA -
F4V39_RS03240 631869..632099 + 231 WP_000916763.1 DNA polymerase III subunit theta -
F4V39_RS03245 632201..632857 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
F4V39_RS03250 632881..633543 + 663 WP_000944244.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T140278 NZ_CP044148:c629968-629865 [Escherichia coli O157]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT140278 NZ_CP044148:629827-630098 [Escherichia coli O157]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References