Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2273113..2273384 | Replicon | chromosome |
| Accession | NZ_CP044145 | ||
| Organism | Escherichia coli O157 strain AR-0428 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2273151..2273254 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2273113..2273384 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F4V40_RS12210 | 2270270..2271709 | + | 1440 | WP_001302304.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| F4V40_RS12215 | 2271827..2272063 | + | 237 | WP_001295499.1 | DUF1480 family protein | - |
| F4V40_RS12220 | 2272168..2272359 | + | 192 | WP_001296140.1 | YebW family protein | - |
| F4V40_RS12225 | 2272360..2273016 | - | 657 | Protein_2309 | protein-serine/threonine phosphatase | - |
| - | 2273113..2273384 | + | 272 | - | - | Antitoxin |
| - | 2273151..2273254 | - | 104 | - | - | Toxin |
| F4V40_RS12230 | 2273412..2273753 | - | 342 | WP_000976483.1 | YebY family protein | - |
| F4V40_RS12235 | 2273766..2274638 | - | 873 | WP_000879314.1 | copper homeostasis membrane protein CopD | - |
| F4V40_RS12240 | 2274642..2275016 | - | 375 | WP_000168751.1 | CopC domain-containing protein YobA | - |
| F4V40_RS12245 | 2275155..2275385 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| F4V40_RS12250 | 2275487..2276143 | + | 657 | WP_000011656.1 | carbon-nitrogen hydrolase family protein | - |
| F4V40_RS12255 | 2276167..2276829 | + | 663 | WP_000944243.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2257272..2295502 | 38230 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T140248 NZ_CP044145:c2273254-2273151 [Escherichia coli O157]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT140248 NZ_CP044145:2273113-2273384 [Escherichia coli O157]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
