Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4717571..4717842 Replicon chromosome
Accession NZ_CP044143
Organism Escherichia coli O157 strain AR-0429

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4717701..4717804 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4717571..4717842 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F4V41_RS24530 4714126..4714788 - 663 WP_000944243.1 exodeoxyribonuclease X -
F4V41_RS24535 4714812..4715468 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
F4V41_RS24540 4715570..4715800 - 231 WP_000916763.1 DNA polymerase III subunit theta -
F4V41_RS24545 4715939..4716313 + 375 WP_000168751.1 CopC domain-containing protein YobA -
F4V41_RS24550 4716317..4717189 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
F4V41_RS24555 4717202..4717543 + 342 WP_000976483.1 YebY family protein -
- 4717571..4717842 - 272 - - Antitoxin
- 4717701..4717804 + 104 - - Toxin
F4V41_RS24560 4717939..4718595 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
F4V41_RS24565 4718596..4718787 - 192 WP_001296140.1 YebW family protein -
F4V41_RS24570 4718892..4719128 - 237 WP_001295499.1 DUF1480 family protein -
F4V41_RS24575 4719246..4720685 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T140226 NZ_CP044143:4717701-4717804 [Escherichia coli O157]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT140226 NZ_CP044143:c4717842-4717571 [Escherichia coli O157]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References