Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4146502..4146773 Replicon chromosome
Accession NZ_CP044140
Organism Escherichia coli O157 strain AR-0430

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4146632..4146735 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4146502..4146773 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F4V42_RS21730 4143057..4143719 - 663 WP_000944243.1 exodeoxyribonuclease X -
F4V42_RS21735 4143743..4144399 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
F4V42_RS21740 4144501..4144731 - 231 WP_000916763.1 DNA polymerase III subunit theta -
F4V42_RS21745 4144870..4145244 + 375 WP_000168751.1 CopC domain-containing protein YobA -
F4V42_RS21750 4145248..4146120 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
F4V42_RS21755 4146133..4146474 + 342 WP_000976483.1 YebY family protein -
- 4146502..4146773 - 272 - - Antitoxin
- 4146632..4146735 + 104 - - Toxin
F4V42_RS21760 4146870..4147526 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
F4V42_RS21765 4147527..4147718 - 192 WP_001296140.1 YebW family protein -
F4V42_RS21770 4147823..4148059 - 237 WP_001295499.1 DUF1480 family protein -
F4V42_RS21775 4148177..4149616 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T140190 NZ_CP044140:4146632-4146735 [Escherichia coli O157]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT140190 NZ_CP044140:c4146773-4146502 [Escherichia coli O157]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References