Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 923681..924563 Replicon plasmid pRPC1
Accession NZ_CP044126
Organism Rhizobium sp. BG4

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag F2982_RS24425 Protein ID WP_203430206.1
Coordinates 923681..924199 (-) Length 173 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag F2982_RS24430 Protein ID WP_130280273.1
Coordinates 924192..924563 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F2982_RS24395 918696..919367 + 672 WP_130280265.1 amino acid ABC transporter permease -
F2982_RS24400 919367..920038 + 672 WP_203430204.1 amino acid ABC transporter permease -
F2982_RS24405 920040..920774 + 735 WP_199625558.1 amino acid ABC transporter ATP-binding protein -
F2982_RS24410 920784..921701 + 918 WP_203430205.1 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase -
F2982_RS24415 921724..922515 + 792 WP_199625560.1 transporter substrate-binding domain-containing protein -
F2982_RS24420 922552..923553 - 1002 WP_199625561.1 LacI family transcriptional regulator -
F2982_RS24425 923681..924199 - 519 WP_203430206.1 RES domain-containing protein Toxin
F2982_RS24430 924192..924563 - 372 WP_130280273.1 DUF2384 domain-containing protein Antitoxin
F2982_RS24435 924643..925425 - 783 WP_203430207.1 crotonase/enoyl-CoA hydratase family protein -
F2982_RS24440 925422..926282 - 861 WP_203430208.1 hydroxymethylglutaryl-CoA lyase -
F2982_RS24445 926279..928258 - 1980 WP_203430209.1 acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA 1..1609137 1609137


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(11-165)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(22-60)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 18935.39 Da        Isoelectric Point: 6.7153

>T140151 WP_203430206.1 NZ_CP044126:c924199-923681 [Rhizobium sp. BG4]
MPDRNSGDILKLWRAFVPRWAFAPLSGEGAARFGGRWNPVGASTIYAARELSTAWAEYNQGFVQHPAIIAQLELAGARLA
DTTASAVLESYGEAADIHRCEWRQELDAGRIPTTHRLRERLIADGFDGVIYPSFMSPGGTCVALWRWNTPGSPELRAIDP
EGRLPKTAASWL

Download         Length: 519 bp

>T140151 NZ_CP058962:29972-30277 [Klebsiella pneumoniae]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGACGAAAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACTTCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 12832.79 Da        Isoelectric Point: 10.3104

>AT140151 WP_130280273.1 NZ_CP044126:c924563-924192 [Rhizobium sp. BG4]
MAAIGLDIAAARFGDGQSAFLSARRVADQLGVTLAELAKLIGVARNTLTAKSSARKVDGALSNVVRILSMASEMAGDDNR
AVIWFKHQPIPGWGGKTAFDLVGEGKSGKVLAYLEAVRSGVYA

Download         Length: 372 bp

>AT140151 NZ_CP058962:29752-29970 [Klebsiella pneumoniae]
ATGAAGCAGCGCATCACTGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTTCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGCTTTATTGAGATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References