Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 1380728..1381296 Replicon chromosome
Accession NZ_CP044125
Organism Rhizobium sp. BG4

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag F2982_RS07210 Protein ID WP_199626080.1
Coordinates 1380728..1381003 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag F2982_RS07215 Protein ID WP_025555372.1
Coordinates 1380988..1381296 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F2982_RS07190 1376468..1377547 - 1080 WP_130279164.1 ABC transporter permease -
F2982_RS07195 1377705..1378724 - 1020 WP_112713623.1 sugar ABC transporter substrate-binding protein -
F2982_RS07200 1378964..1380211 + 1248 WP_199626081.1 ROK family protein -
F2982_RS07205 1380195..1380677 + 483 WP_025555520.1 transporter -
F2982_RS07210 1380728..1381003 + 276 WP_199626080.1 BrnT family toxin Toxin
F2982_RS07215 1380988..1381296 + 309 WP_025555372.1 BrnA antitoxin family protein Antitoxin
F2982_RS07220 1381312..1382349 - 1038 WP_199626079.1 proline racemase family protein -
F2982_RS07225 1382392..1383642 - 1251 WP_203429670.1 FAD-binding oxidoreductase -
F2982_RS07230 1383728..1385002 - 1275 WP_112713629.1 alpha/beta hydrolase -
F2982_RS07235 1385159..1385542 + 384 WP_025555417.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-82)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(23-100)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10479.97 Da        Isoelectric Point: 9.5647

>T140147 WP_199626080.1 NZ_CP044125:1380728-1381003 [Rhizobium sp. BG4]
MKIVWDEPKRQSNLDKHGFDFADVDELDWRRAVIEVTKPDAEGKQRMKAIGYYRDGTAVVIFATLGNEAISVISFRKANA
KERSKLEWPKP

Download         Length: 276 bp

>T140147 NZ_CP058960:c5078744-5077827 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGTGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11503.12 Da        Isoelectric Point: 10.0904

>AT140147 WP_025555372.1 NZ_CP044125:1380988-1381296 [Rhizobium sp. BG4]
MAKTLKTFQPGRGYSKDDWDAVDSPPLTDEELAAMRPAQDVLPKAFFDAMDEHRRARGRPPIEHPKKQITLRIDEDVVAK
FRESGKGWQGRMNAALRKAAGL

Download         Length: 309 bp

>AT140147 NZ_CP058960:c5079508-5078750 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGTCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References