140143

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 554977..555611 Replicon chromosome
Accession NZ_CP044125
Organism Rhizobium sp. BG4

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag F2982_RS02970 Protein ID WP_203430001.1
Coordinates 555243..555611 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag F2982_RS02965 Protein ID WP_112719547.1
Coordinates 554977..555240 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F2982_RS02945 550040..551443 + 1404 WP_112719543.1 DNA repair protein RadA -
F2982_RS02950 551538..552167 + 630 WP_112719544.1 CvpA family protein -
F2982_RS02955 552340..553830 + 1491 WP_203429179.1 amidophosphoribosyltransferase -
F2982_RS02960 554173..554913 + 741 WP_112719546.1 SDR family NAD(P)-dependent oxidoreductase -
F2982_RS02965 554977..555240 + 264 WP_112719547.1 PbsX family transcriptional regulator Antitoxin
F2982_RS02970 555243..555611 + 369 WP_203430001.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
F2982_RS02975 555608..556258 - 651 WP_203430002.1 glycosyl hydrolase -
F2982_RS02980 556683..558059 + 1377 WP_203429180.1 cysteine--tRNA ligase -
F2982_RS02985 558265..558741 + 477 WP_203429181.1 GFA family protein -
F2982_RS02990 558738..559226 + 489 WP_203429182.1 GFA family protein -
F2982_RS02995 559223..559699 + 477 WP_203429183.1 GFA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13228.11 Da        Isoelectric Point: 7.2781

>T140143 WP_203430001.1 NZ_CP044125:555243-555611 [Rhizobium sp. BG4]
MVRSNVPKRGDVYWIDPHPVAGREMKNRHRFVVITPREINALGVSMTVPITNGGAFTRDVGLAVAISGHDTTGVAVCNQV
RSFDIAARIQQKTAQYIETLDEATMSEIVARVVSAIDPAPEG

Download         Length: 369 bp

>T140143 NZ_CP058960:c2720252-2718930 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCTGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9286.65 Da        Isoelectric Point: 4.7719

>AT140143 WP_112719547.1 NZ_CP044125:554977-555240 [Rhizobium sp. BG4]
MSITTKIRRQGGAAIVTLPPAVLKMMQVEVGDQLSLDVANGELIGRATRPAKKRYSLSELLEGADEIRALNAEVADAQDG
DPVGREI

Download         Length: 264 bp

>AT140143 NZ_CP058960:c2720518-2720252 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References