140138

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 401265..401812 Replicon chromosome
Accession NZ_CP044123
Organism Agrobacterium rhizogenes strain LBA9402

Toxin (Protein)


Gene name parE Uniprot ID A0A5M8UJE8
Locus tag F3X89_RS21055 Protein ID WP_037222627.1
Coordinates 401519..401812 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID B9JNC7
Locus tag F3X89_RS21050 Protein ID WP_012649398.1
Coordinates 401265..401519 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F3X89_RS21025 396641..396952 - 312 WP_012649393.1 hypothetical protein -
F3X89_RS21030 397081..399015 - 1935 WP_047469545.1 heavy metal translocating P-type ATPase -
F3X89_RS21035 399426..399725 + 300 WP_034522626.1 hypothetical protein -
F3X89_RS21040 399737..400165 + 429 WP_034522328.1 universal stress protein -
F3X89_RS21045 400720..400944 - 225 WP_110924608.1 ATP-binding domain-containing protein -
F3X89_RS21050 401265..401519 + 255 WP_012649398.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
F3X89_RS21055 401519..401812 + 294 WP_037222627.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F3X89_RS21060 402255..403247 + 993 WP_131596068.1 nucleotidyltransferase family protein -
F3X89_RS21065 403244..404323 - 1080 WP_041723665.1 transporter -
F3X89_RS21070 404344..404568 - 225 WP_007689697.1 hypothetical protein -
F3X89_RS21075 405151..405372 + 222 WP_007689698.1 hypothetical protein -
F3X89_RS21080 405562..406026 + 465 WP_012649402.1 VOC family protein -
F3X89_RS21085 406055..406393 - 339 WP_007689700.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-92)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11208.78 Da        Isoelectric Point: 5.9024

>T140138 WP_037222627.1 NZ_CP044123:401519-401812 [Agrobacterium rhizogenes]
MRFSLFVEAEEDIIAIAEQGVRLFGSAHAKRYHDELFSLLDLIAANPRMAREREEISPPVRIHPFKAHLVVYRIEEDGAI
FVIRIRHGHEDWASDSV

Download         Length: 294 bp

>T140138 NZ_CP058960:324617-324985 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9362.53 Da        Isoelectric Point: 8.5688

>AT140138 WP_012649398.1 NZ_CP044123:401265-401519 [Agrobacterium rhizogenes]
MATMNVSLPDPMKDWVEAQAKTGRYSNASDYVRDLIRRDQVRSDKIAAMQRFVDDGLKSGVGGRSKDELFATAIAHGEMT
RGDR

Download         Length: 255 bp

>AT140138 NZ_CP058960:324399-324620 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5M8UJE8

Antitoxin

Source ID Structure
AlphaFold DB A0A5M8UM94

References