Detailed information of TA system TA140135

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii(toxin)
• Location: 3520908..3522384
• Replicon: chromosome
• Accession: NZ_CP044122
• Organism: Agrobacterium rhizogenes strain LBA9402

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: F3X89_RS17100
• Protein ID: WP_034516990.1
• Coordinates: 3521518..3522384 (+)
• Length: 289 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: F3X89_RS17095
• Protein ID: WP_034516992.1
• Coordinates: 3520908..3521525 (+)
• Length: 206 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F3X89_RS17090	3520550..3520690	+	141	WP_153511264.1	hypothetical protein	-
F3X89_RS17095	3520908..3521525	+	618	WP_034516992.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
F3X89_RS17100	3521518..3522384	+	867	WP_034516990.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
F3X89_RS17105	3522763..3524157	-	1395	WP_034516988.1	hypothetical protein	-
F3X89_RS17110	3524616..3525182	+	567	WP_082007195.1	DUF746 domain-containing protein	-
F3X89_RS17115	3525368..3526048	+	681	WP_012650670.1	invasion associated locus B family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-260)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (16-55)

Sequences

Toxin

Protein

• Length: 289 a.a.
• Molecular weight: 32351.95 Da
• Isoelectric Point: 5.2615

>T140135 WP_034516990.1 NZ_CP044122:3521518-3522384 [Agrobacterium rhizogenes]
MAKEIKNIGASVRARLLQLAKASGQSFDLVLTRFALERLLFRLSRSSHADRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
DPSAELMLATFREILAQDASDGVEFDADALRVDRIREELEYGGLRLRTTASISGARISLTIDIGFGDALEPGTEELDYPS
MLDFPMPRLRGYARETVIAEKFQAMVALGRANTRMKDFYDIWILSRSFDFSNDRLVRAITGTFERRETPIPTVLPDALTE
AFAQDQQKQRQWRAFVEDVAHNPGELMDVITDIAGFLMPHAAAASRGK

Nucleotide

• Length: 867 bp

>T140135 NZ_CP058958:c4085646-4085323 [Providencia rettgeri]
TTGACTCAGAAGCCAAGTAATAAGCGAGCTAAGCAACCAAGGCAGGTTGCTTATACACCAACGTTTAAGGAGTCATGGGA
ACGATATAACCGAGCGGGCCGTAGGGATATGAATGCGGCTGTTCTCGTTATGGAAATACTGTTTTCTCAAAAAATAATAC
CAAAAGAATATCTTGACCATGAATTAGAAGGTCATGAATGGCAAGGAGCTAGGGAGCTTCATATTGGTGGTGATTTCTTA
CTGGTTTATCGCTTGTCAGATAAAGGTAATTTAATCACTTTCGTTGATATTGGTTCGCACAGTGAATTATTTGGTGTAAG
GTAA

Antitoxin

Protein

• Length: 206 a.a.
• Molecular weight: 22434.05 Da
• Isoelectric Point: 10.2836

>AT140135 WP_034516992.1 NZ_CP044122:3520908-3521525 [Agrobacterium rhizogenes]
MPESISQRQIAHALLTARGIARLVELRDAGVTAATMSRMERDGEVLRLARGLYQLSDAPLDANHSLAEAAKRLPKGVVCL
VSALAFHGLTDQLPKQVWLAIGRKDWAPKPDSTPIRIVRFTDRLLNESVETHVVEGVPVKVFGIVKTIADCFRYRNKIGL
SVAIEGLQEVLRQRKATPGEIARQAERGGVATVIRPYIEALTANG

Nucleotide

• Length: 618 bp

>AT140135 NZ_CP058958:c4085914-4085627 [Providencia rettgeri]
ATGTCAACACTATTGAAAACAACAGATGTTCGTAGTCGAATTGATGAACAATTAAAAGCGGAAGCCACGAGTGTATTACA
AGATTGTGGTTTGACTATTAGCGCAGCTATTCGTTTGTTTTTAGAACAAGTAGTTCAAGAGCAAAGAGTTCCCTTTGAAA
TAAAACGTAAGCAACCTTCGCTGAAAACTACACTAGCGTTGAAAGAAGCTAAAGCTATTGAGCAGCACTACGATTCAATT
AACGAAATGATGGTGGAGTTAAGCAAAGTTGACTCAGAAGCCAAGTAA