Detailed information of TA system TA140134

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbE-relB/ParE-YafN
• Location: 2816852..2817371
• Replicon: chromosome
• Accession: NZ_CP044122
• Organism: Agrobacterium rhizogenes strain LBA9402

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: F3X89_RS13890
• Protein ID: WP_047468554.1
• Coordinates: 2817090..2817371 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: B9JBR8
• Locus tag: F3X89_RS13885
• Protein ID: WP_012652580.1
• Coordinates: 2816852..2817100 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F3X89_RS13860	2812541..2813488	+	948	WP_065707345.1	ABC transporter permease	-
F3X89_RS13865	2813573..2814280	+	708	WP_065707362.1	YdcF family protein	-
F3X89_RS13870	2814379..2815179	+	801	WP_012652577.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
F3X89_RS13875	2815176..2815709	-	534	WP_012652578.1	gamma-glutamylcyclotransferase	-
F3X89_RS13880	2815761..2816774	+	1014	WP_047468551.1	DUF2125 domain-containing protein	-
F3X89_RS13885	2816852..2817100	+	249	WP_012652580.1	antitoxin	Antitoxin
F3X89_RS13890	2817090..2817371	+	282	WP_047468554.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
F3X89_RS13895	2817418..2818347	-	930	WP_012652582.1	prephenate/arogenate dehydrogenase family protein	-
F3X89_RS13900	2818344..2819453	-	1110	WP_047468556.1	histidinol-phosphate transaminase	-
F3X89_RS13905	2819557..2820336	-	780	WP_007693610.1	class I SAM-dependent methyltransferase	-
F3X89_RS13910	2820392..2821162	+	771	WP_007693609.1	hydroxyacylglutathione hydrolase	-
F3X89_RS13915	2821162..2821587	+	426	WP_034521573.1	cupin domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (8-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11054.88 Da
• Isoelectric Point: 10.6226

>T140134 WP_047468554.1 NZ_CP044122:2817090-2817371 [Agrobacterium rhizogenes]
MTYELGFLHAALKEWRKLDANTREQFKKKLAERCENPRVPSAKLFGSKDRYKIKLRGVGYRLVYEVRDEQLVIIVVAVGK
RERNEIYRAADRR

Nucleotide

• Length: 282 bp

>T140134 NZ_CP058958:2911675-2911983 [Providencia rettgeri]
ATGCAATATTGCCTCTATCAAAACCGAGAAGATACGGTCAAATACCCATATTTACTGGATATTCAAAGTAACATTATTGA
TATATTGAATACTCGTTTAGTCATCCCGTTATTCGATAGCAGGCTAGTTAAAAAGCCATTACCTGTACGCTTAAATCCCC
AATTAGTTATCAACGAGCAGGTTTTTATTTTAATGACTCACCAAATGGCTTGCGTCCCTCATTCATTATTAGGGAAAGAA
ATCGTTGACTTAAGTAGCCAGCGAGACACCATTAAACACGCAATTGACTTACTGATTGATGGCTTTTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8775.18 Da
• Isoelectric Point: 4.3466

>AT140134 WP_012652580.1 NZ_CP044122:2816852-2817100 [Agrobacterium rhizogenes]
MTNVILAEVTASVSELKKNPMGTVAAGEGATVAILNRNAPAFYCVPARLYEAMLDRLEDMELNAIADARAGEPIIKVKLD
DL

Nucleotide

• Length: 249 bp

>AT140134 NZ_CP058958:2911448-2911675 [Providencia rettgeri]
ATGAATAGAACAAAAAAAACCGTCAGTGTCACTGTCGCGCCTGAACTCTACGAACAAGCAAGGCGGGCTAAACTTAACTT
ATCAGCAATACTGGCTTGTGCCTTACAAGCTGAATTAAAACGCCTCGAAGCGCAAAAATGGAAAAATGACAATGTCGAAG
GCTTTAATGAGTTAAACAGGATAAATGAAGAATATGGATTACTCTCAGATAAATACAAGGATTTTTAA

Structures

Antitoxin

• AlphaFold DB: A0A5M8UL61