Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 4936616..4937195 Replicon chromosome
Accession NZ_CP044121
Organism Raoultella planticola strain S25

Toxin (Protein)


Gene name shpA Uniprot ID A0A8G2A7B0
Locus tag F3X94_RS23825 Protein ID WP_032689636.1
Coordinates 4936616..4936903 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag F3X94_RS23830 Protein ID WP_150341518.1
Coordinates 4936890..4937195 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F3X94_RS23795 4931958..4932476 - 519 WP_032689643.1 hypothetical protein -
F3X94_RS23800 4932473..4933285 - 813 WP_094898375.1 winged helix-turn-helix domain-containing protein -
F3X94_RS23805 4933428..4934006 - 579 WP_032689640.1 TetR/AcrR family transcriptional regulator -
F3X94_RS23810 4934133..4934936 - 804 WP_032697902.1 NAD(P)H-dependent oxidoreductase -
F3X94_RS23815 4935024..4935932 + 909 WP_032698239.1 LysR family transcriptional regulator -
F3X94_RS23820 4935926..4936369 + 444 WP_032689637.1 FosA family fosfomycin resistance glutathione transferase -
F3X94_RS23825 4936616..4936903 + 288 WP_032689636.1 BrnT family toxin Toxin
F3X94_RS23830 4936890..4937195 + 306 WP_150341518.1 BrnA antitoxin family protein Antitoxin
F3X94_RS23835 4937351..4938763 - 1413 WP_032697905.1 PLP-dependent aminotransferase family protein -
F3X94_RS23840 4938941..4939105 + 165 WP_064497381.1 DUF1127 domain-containing protein -
F3X94_RS23845 4939396..4939860 + 465 WP_032689634.1 MarR family transcriptional regulator -
F3X94_RS23850 4939867..4940934 + 1068 WP_032689633.1 HlyD family secretion protein -
F3X94_RS23855 4940924..4941988 + 1065 WP_032689632.1 DUF2955 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(40-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11146.59 Da        Isoelectric Point: 7.5232

>T140132 WP_032689636.1 NZ_CP044121:4936616-4936903 [Raoultella planticola]
MPMEFEWDANKATSNLKKHGIRFEEAVLVFDDPQHLSRHDRYENGEYRWQTIGLVHGVIVVLVAHSVRFESGTEVIRIIS
ARKADKKERNRYEHG

Download         Length: 288 bp

>T140132 NZ_CP058958:c1768523-1768338 [Providencia rettgeri]
GTGCAAAGTTCGGAACTGATAAACATACTGCAAAAAAACGGTTGGAAACTTGAAAGAATAAAAGGAAGTCACCATCAGTT
TTCCCACCCACATTTTTCAATTGTAATTACTGTTCCGCATCCACAAAAAGATTTAAAGATAGGCACACTAAATCACATTT
TGAAGGCTGCGAAACTAAAACATTAA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11668.13 Da        Isoelectric Point: 8.4533

>AT140132 WP_150341518.1 NZ_CP044121:4936890-4937195 [Raoultella planticola]
MNMVKHKRDNPTALTAQREDELNALAKKSDDDIDYSDIPSSDDEAWSEAVRGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKKS

Download         Length: 306 bp

>AT140132 NZ_CP058958:c1768288-1767875 [Providencia rettgeri]
ATGCTTTATACCGCCTTTATTGAAATTGATAATGATGGCAGCGCAAGTGGCTGGTTTCCTGATATTGAAGGATGTACATT
CGCGGGCAGCAATATAGAAGAGGCTTACGCAGAAGCAAAATCAGCAATTGATGCTCATTTTGAATTATTGAGTGAAAAAG
GCTTCGAGATCCCATTATCGAAATCTCAGCAAACGCTATTGAACCCAATACAACCTGAATATGCGCATGGGATATGGTTA
TTTGTGGATGTCGATATGGATAAATACGATGGCCGTACTGAGCGTATTAATATCACCTTGCCGCATCGTTTATTACATCG
TATTGATGCTTTAGTGAAGGTTAATCCTGAATATGGTAGCCGTAGTGGTTTTATTGCTGCTGCAACTCGTAAAGAATTAA
AAAAAACCGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References