Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 2254533..2255259 Replicon chromosome
Accession NZ_CP044107
Organism Enterobacter hormaechei strain FDAARGOS_642

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag FOB50_RS10810 Protein ID WP_072035667.1
Coordinates 2254533..2254862 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag FOB50_RS10815 Protein ID WP_042893201.1
Coordinates 2254900..2255259 (-) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB50_RS10795 2250720..2251619 - 900 WP_017692842.1 carbohydrate ABC transporter permease -
FOB50_RS10800 2251619..2252596 - 978 WP_150390965.1 sugar ABC transporter permease -
FOB50_RS10805 2252664..2253902 - 1239 WP_150390966.1 ribokinase -
FOB50_RS10810 2254533..2254862 - 330 WP_072035667.1 TA system toxin CbtA family protein Toxin
FOB50_RS10815 2254900..2255259 - 360 WP_042893201.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
FOB50_RS10820 2255282..2255503 - 222 WP_042893203.1 DUF987 domain-containing protein -
FOB50_RS10825 2255518..2255997 - 480 WP_042893205.1 DNA repair protein RadC -
FOB50_RS10830 2256009..2256404 - 396 WP_045341441.1 antirestriction protein -
FOB50_RS10835 2256420..2256674 - 255 WP_072035668.1 hypothetical protein -
FOB50_RS10840 2256674..2257492 - 819 WP_150390967.1 DUF945 domain-containing protein -
FOB50_RS10845 2257590..2257823 - 234 WP_042893208.1 DUF905 family protein -
FOB50_RS10850 2257917..2258753 - 837 WP_042893210.1 hypothetical protein -
FOB50_RS22345 2258811..2258975 - 165 WP_154816236.1 hypothetical protein -
FOB50_RS10855 2259056..2259283 - 228 WP_042893214.1 hypothetical protein -
FOB50_RS10860 2259356..2259763 - 408 WP_150390968.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(15-115)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12450.17 Da        Isoelectric Point: 10.5232

>T140108 WP_072035667.1 NZ_CP044107:c2254862-2254533 [Enterobacter hormaechei]
MQTLSSHSTRATQPNLSPVKTWQRLLTHLLSQHYGLRLNDTPFSNETTIREHIDAGVSLSDAVNFLVEKYGLVRIDRKGF
SWQEQTPYISVVDILRARRSTGLLKTNVK

Download         Length: 330 bp

>T140108 NZ_CP058948:c1703242-1703135 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13412.23 Da        Isoelectric Point: 5.8752

>AT140108 WP_042893201.1 NZ_CP044107:c2255259-2254900 [Enterobacter hormaechei]
MQNTTPVANHDIAEPWWGLKPTVTPCLGARLVQEGNRLHYLADPASITGTFNNEDLRHLDQAFPVLLKQLELMLVSGELT
SRYQHRITLYHNRLTCEADTLGSCGYVCIAIYPDQPEPH

Download         Length: 360 bp

>AT140108 NZ_CP058948:1703289-1703355 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References