Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB(antitoxin)
Location 396081..396699 Replicon chromosome
Accession NZ_CP044102
Organism Streptococcus dysgalactiae strain FDAARGOS_654

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FOB62_RS01905 Protein ID WP_003058081.1
Coordinates 396358..396699 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FOB62_RS01900 Protein ID WP_003058067.1
Coordinates 396081..396368 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB62_RS01870 391389..391661 + 273 WP_003058046.1 hypothetical protein -
FOB62_RS01875 391671..391934 + 264 WP_003058063.1 hypothetical protein -
FOB62_RS01880 391947..392888 + 942 WP_003058075.1 conjugal transfer protein -
FOB62_RS01885 392885..393103 + 219 WP_003058071.1 hypothetical protein -
FOB62_RS01890 393112..393528 + 417 WP_003058056.1 conjugal transfer protein -
FOB62_RS01895 393512..396010 + 2499 WP_003058044.1 ATP-binding protein -
FOB62_RS01900 396081..396368 + 288 WP_003058067.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FOB62_RS01905 396358..396699 + 342 WP_003058081.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOB62_RS01910 396757..398658 + 1902 WP_150336161.1 hypothetical protein -
FOB62_RS01915 398661..399764 + 1104 WP_014612121.1 CHAP domain-containing protein -
FOB62_RS01920 399784..399981 + 198 WP_003058094.1 transposase -
FOB62_RS01925 399992..401236 + 1245 WP_014612120.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - tufA 287869..436349 148480


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-100)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-90)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13438.41 Da        Isoelectric Point: 7.0067

>T140085 WP_003058081.1 NZ_CP044102:396358-396699 [Streptococcus dysgalactiae]
MAYNVQITKSAERDLDSIYQFYLDEFSEQSALKVIKSLQDAISFLYVSPLGYTDFDSKINRKIYPQGNLRMIPSKQYLIF
YLIREERVDVLRIIHSRTDYLNNLENLFKNLNL

Download         Length: 342 bp

>T140085 NZ_CP058907:3870467-3870661 [Rhodopseudomonas palustris]
ATGCTCACCAGTAGCCGCGATGTCATCCGACGTCTCGAACGTGACGGCTGGAGTTGCGTCCGCGTCACGGGATCGCATCA
CGTCTTCAAGCATCCTGTGCGCCGGGACATCGTCACCGTGCCGCATCCCAAGAAGGACTTGGGAAAAGGCTTGGTCCGTG
CCATTTATAAGGGCGCAGGCTGGGAGCCGGATTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10869.33 Da        Isoelectric Point: 4.3885

>AT140085 WP_003058067.1 NZ_CP044102:396081-396368 [Streptococcus dysgalactiae]
MNTLARDRQYNFRVNADMLNQAKEILEEKHMSLPDALNLFVEQVVVTKDLPIKTPEQVQAESFLNELISELDEGYQDVLK
GNTKPANEVFAKYGL

Download         Length: 288 bp

>AT140085 NZ_CP058907:3870670-3870960 [Rhodopseudomonas palustris]
ATGACCCACTACATCGCTATCATCGAAGATGCCGGGCCGGACGTGGCGGTCGGGGTGTGGTTTCCGGACCTGCCCGGCTG
CGTCTCCGCCGGCGATGACATCGACGACGCCCTGCGCAATGCGCCGGAGGCGCTGGAGCTGTATCTCGAGCAGGTCGAGC
AGGACGGCAGGCCGCTGCCGAAGCCTCGCACACTAACTGAGCTGAAGGCCGACCCCGAAGTCGCGGACGACATTCGGGAT
TACATCGTCGCGCTGATCGAAACGCCGACCCGCGCCCACGCGGCGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References