Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3293714..3294368 Replicon chromosome
Accession NZ_CP044098
Organism Citrobacter portucalensis strain FDAARGOS_617

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FOB25_RS15780 Protein ID WP_003825515.1
Coordinates 3293961..3294368 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FOB25_RS15775 Protein ID WP_003825514.1
Coordinates 3293714..3293980 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB25_RS15745 3288868..3290301 - 1434 WP_032944895.1 6-phospho-beta-glucosidase BglA -
FOB25_RS15750 3290423..3291151 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
FOB25_RS15755 3291204..3291515 + 312 WP_008785743.1 N(4)-acetylcytidine aminohydrolase -
FOB25_RS15760 3291679..3292341 + 663 WP_006686898.1 hemolysin III family protein -
FOB25_RS15765 3292473..3293456 - 984 WP_032944893.1 tRNA-modifying protein YgfZ -
FOB25_RS15775 3293714..3293980 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
FOB25_RS15780 3293961..3294368 + 408 WP_003825515.1 protein YgfX Toxin
FOB25_RS15785 3294470..3294991 - 522 WP_003026933.1 flavodoxin FldB -
FOB25_RS15790 3295105..3296001 + 897 WP_003825519.1 site-specific tyrosine recombinase XerD -
FOB25_RS15795 3296025..3296738 + 714 WP_003825520.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FOB25_RS15800 3296744..3298477 + 1734 WP_032944891.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15882.76 Da        Isoelectric Point: 11.3523

>T140059 WP_003825515.1 NZ_CP044098:3293961-3294368 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T140059 NZ_CP058886:c724372-724076 [Shigella flexneri]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT140059 WP_003825514.1 NZ_CP044098:3293714-3293980 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT140059 NZ_CP058886:c724074-723679 [Shigella flexneri]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References